The production of harmful free radicals (H-FRs), especially those with oxygen or nitrogen
atoms, depends on both internal and environmental causes. The negative effects of H-FRs …

Vascular calcification is a common accompanying pathological change in many chronic
diseases, which is caused by calcium deposition in the blood vessel wall and leads to …

Regular exercise and physical activity are now considered lifestyle factors with positive
effects on human health. Physical activity reduces disease burden, protects against the …

The relationship between exercise and obesity has attracted increasing attention from
researchers worldwide in recent years. The aim of the present study was to analyze the …

Irisin-based interventions have gained attention for their potential to modulate the adenosine
monophosphate (AMP)-activated protein kinase (AMPK) pathway in various diseases …

This study aimed to analyze the acute impact of exercise on serum irisin levels in 22 young
(YA, 24.6±3.5 yrs) and in 12 middle-aged male adults (MA, 54.6±5.7 yrs) 15 min and 24 h …

Introduction Exercise has been recognized to improve cognitive performance by optimizing
gut flora and up-regulating exerkine irisin. Objective Although exercise-induced irisin is …

The current study focused on identifying the potential of irisin in mammalian reproduction.
The established role of irisin, a proteolytic product of FNDC5, in adipose tissue browning …

Lifestyle factors, particularly physical inactivity, are closely linked to the onset of numerous
metabolic diseases. Adipose tissue (AT) has been extensively studied for various metabolic …

Skeletal muscle plays a vital role in the regulation of systemic metabolism, partly through its
secretion of endocrine factors which are collectively known as myokines. Altered myokine …