The advancement in nanotechnology has completely revolutionized various fields, including
pharmaceutical sciences, and streamlined the potential therapeutic of many diseases that …

Polyphenols have received considerable attention for their promotive effects on colonic
health. However, polyphenols are mostly sensitive to harsh gastrointestinal environments …

In the present study, polymeric nanoparticles loaded with IRI and quercetin, a p-gp inhibitor,
were developed to target folate receptors expressed by colon cancer cells for oral targeted …

Metabolic syndrome (MetS) is a diseased condition incorporating the abnormal
accumulation of various metabolic components, including overweight or abdominal obesity …

Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway,
essential for cellular communication, orchestrates a myriad of physiological and pathological …

The study aimed to develop and evaluate chitosan-based nanoparticles coated with TPGS
for the targeted delivery of imatinib mesylate to colon cancer cells. Particle size and zeta …

Colorectal cancer (CRC) is an abnormal proliferation of cells within the colon and rectum,
leading to the formation of polyps and disruption of mucosal functions. The disease …

Naringenin, a natural dihydrochalcone flavonoid, exhibits diverse pharmacological
properties. This study investigates the hypolipidemic effects of Nar-NPs on obese mice. The …

Nitrofurantoin (NTF) is a first-line therapy for treating urinary tract infections. However, gastric
upset, short half-life, and poor bioavailability of NTF are major challenges for clinical use …