Association of high-risk stigmata and worrisome features with advanced neoplasia in intraductal papillary mucinous neoplasms (IPMN): A systematic review

E Ohno, A Balduzzi, S Hijioka, M De Pastena… - Pancreatology, 2024 - Elsevier
Background This systematic review aimed to assess the diagnostic accuracy of the
International Consensus Fukuoka Guidelines (ICG2017) in identifying high-risk lesions of …

The tumour immune microenvironment and microbiome of pancreatic intraductal papillary mucinous neoplasms

T Pollini, V Adsay, G Capurso, M Dal Molin… - The Lancet …, 2022 - thelancet.com
Pancreatic intraductal papillary mucinous neoplasms (IPMNs) have gained substantial
attention because they represent one of the only radiographically identifiable precursors of …

Management of intraductal papillary mucinous neoplasms: controversies in guidelines and future perspectives

IJM Levink, MJ Bruno, DL Cahen - Current treatment options in …, 2018 - Springer
Purpose of review Management of intraductal papillary mucinous neoplasm (IPMN) is
currently based on consensus, in the absence of evidence-based guidelines. In recent …

What is the incidence of malignancy in resected intraductal papillary mucinous neoplasms? An analysis of over 100 US institutions in a single year

RE Khoury, C Kabir, VK Maker, M Banulescu… - Annals of Surgical …, 2018 - Springer
Background A subset of intraductal papillary mucinous neoplasms (IPMNs) will progress to
invasive adenocarcinoma, however identifying invasive from non-invasive disease …

The Landmark Series: Intraductal Papillary Mucinous Neoplasms of the Pancreas—From Prevalence to Early Cancer Detection

T Pollini, P Wong, AV Maker - Annals of Surgical Oncology, 2023 - Springer
Modern series report a prevalence of pancreatic cysts in the general population of up to 50%
in prospective studies. Of these, about half will be pancreatic cystic neoplasms (PCNs) that …

GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal …

T Hata, M Mizuma, F Motoi, Y Omori, M Ishida… - Scientific reports, 2020 - nature.com
Pancreatic cystic neoplasms (PCNs) are a heterogeneous group with varying risks of
malignancy. To explore the clinical utility of liquid biopsy in cyst type classification, we …

Cyst fluid biosignature to predict intraductal papillary mucinous neoplasms of the pancreas with high malignant potential

AV Maker, V Hu, SS Kadkol, L Hong… - Journal of the …, 2019 - journals.lww.com
BACKGROUND: Current standard-of-care technologies, such as imaging and cyst fluid
analysis, are unable to consistently distinguish intraductal papillary mucinous neoplasms …

Multi-omic biomarkers as potential tools for the characterisation of pancreatic cystic lesions and cancer: innovative patient data integration

LE Kane, GS Mellotte, KC Conlon, BM Ryan, SG Maher - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic cancer (PC) is among the most aggressive types of cancer,
having caused over 495,000 deaths worldwide in 2020, with increasing annual incidence …

Multi-omic markers of Intraductal Papillary Mucinous Neoplasms progression into pancreatic cancer

C Corradi, M Gentiluomo, V Adsay, J Sainz… - Seminars in Cancer …, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal and common form of
pancreatic cancer, it has no specific symptoms, and most of the patients are diagnosed …

Determining the role of adjuvant therapy in invasive intraductal papillary mucinous neoplasms; a systematic review and meta-analysis

DL Hughes, I Hughes, MA Silva - European Journal of Surgical Oncology, 2022 - Elsevier
Background Conflicting evidence exists regarding the role of adjuvant therapy for Invasive
Intraductal Papillary Mucinous Neoplasms (i-IPMN). This meta-analysis assessed whether …