Introduction Leishmaniasis is a major public health problem and the second most lethal
parasitic disease in the world due to the lack of effective treatments and vaccines. Even …

Introduction The leishmaniases represent a group of parasitic diseases caused by infection
with one of several species of Leishmania parasites. Disease presentation varies because …

Leishmaniasis is a neglected protozoan disease affecting over 12 million people globally
with no approved vaccines for human use. New World cutaneous leishmaniasis (CL) caused …

The leishmanin skin test was used for almost a century to detect exposure and immunity to
Leishmania, the causative agent of leishmaniasis, a major neglected tropical disease. Due …

Centrin1 gene deleted Leishmania donovani parasite (LdCen1−/−) was developed and
extensively tested experimentally as an intracellular stage-specific attenuated and …

Leishmaniasis, caused by an infection of the Leishmania protozoa, is a neglected tropical
disease and a major health problem in tropical and subtropical regions of the world, with …

Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and
mortality in low and middle-income countries (LMIC). However, this disease is also …

Understanding the unique metabolic pathway of L. donovani is crucial for comprehending its
biology under oxidative stress conditions. The de novo cysteine biosynthetic pathway of L …

Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still
lacking a safe and effective vaccine for humans. Given this scenario, the search for a new …

Introduction Leishmaniasis is a neglected tropical disease that is defined by the World
Health Organization as vaccine preventable. Although several new candidate vaccines are …