Triple-negative breast cancer (TNBC) encompasses a heterogeneous group of
fundamentally different diseases with different histologic, genomic, and immunologic …

Metaplastic breast carcinomas (MPBC) are rare, aggressive and relatively chemorefractory
tumors with a high unmet need. While most are “triple negative” and lack expression of …

Metaplastic breast carcinoma (MBC) is relatively rare but accounts for a significant
proportion of global breast cancer mortality. This group is extremely heterogeneous and by …

Spatially resolved gene expression profiling provides insight into tissue organization and
cell–cell crosstalk; however, sequencing-based spatial transcriptomics (ST) lacks single-cell …

Breast cancer is the most commonly diagnosed cancer type and the leading cause of cancer-
related mortality in women worldwide. Breast cancer is fairly heterogeneous and reveals six …

Rare subtypes of triple-negative breast cancers (TNBC) are a heterogenous group of
tumors, comprising 5–10% of all TNBCs. Despite accounting for an absolute number of …

Metaplastic breast carcinomas comprise a histologically heterogenous group of tumors.
Although most are triple (estrogen/progesterone receptor, HER2) negative, these rare …

Metaplastic breast carcinoma (MBC) is a heterogeneous group of infrequent invasive
carcinomas that display differentiation of the neoplastic epithelium towards squamous cells …

TSC2 is a tumor suppressor gene as well as a disease-causing gene for autosomal
dominant disorder tuberous sclerosis complex (TSC). Research has found that some tumor …

Metaplastic breast cancers (MBC) encompass a group of highly heterogeneous tumors
which share the ability to differentiate into squamous, mesenchymal or neuroectodermal …