Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …

Autophagy is a ubiquitous cellular process that regulates cell growth, survival, development
and death. Its process is closely associated with diverse conditions, such as liver diseases …

Our recently published research on the characterization of vesicular stomatitis virus (VSV)
pathogenesis in swine, identified a systemic upregulation of interleukin 6 (IL-6) during the …

Mycobacterium tuberculosis, a major global health threat, replicates in macrophages in part
by inhibiting phagosome–lysosome fusion, until interferon-γ (IFNγ) activates the …

How exercise elicits systemic metabolic benefits in both muscles and non-contractile tissues
is unclear. Autophagy is a stress-induced lysosomal degradation pathway that mediates …

Autophagy is a complicated cellular mechanism that maintains cellular and tissue
homeostasis and integrity via degradation of senescent, defective subcellular organelles …

Tuberculosis (TB) is one of the oldest known human diseases and is transmitted by the
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …

Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

Research in recent years has focused significantly on the role of selective macroautophagy
in targeting intracellular pathogens for lysosomal degradation, a process termed xenophagy …