Chiral recognition by enantioselective liquid chromatography: mechanisms and modern chiral stationary phases

M Lämmerhofer - Journal of Chromatography A, 2010 - Elsevier
An overview of the state-of-the-art in LC enantiomer separation is presented. This tutorial
review is mainly focused on mechanisms of chiral recognition and enantiomer distinction of …

Modelling approaches for chiral chromatography on polysaccharide-based and macrocyclic antibiotic chiral selectors: A review

P De Gauquier, K Vanommeslaeghe… - Analytica Chimica …, 2022 - Elsevier
An overview of molecular modelling approaches, related to chiral separations on
polysaccharide-based and macrocyclic antibiotic chiral selectors, is presented. Both …

Chiral separations: fundamental review 2010

TJ Ward, KD Ward - Analytical chemistry, 2010 - ACS Publications
This fundamental review article covers developments and applications in chiral separations
from January 2008 to January 2010 and is restricted to the English language literature …

Intelligent Recommendation Systems Powered by Consensus Neural Networks: The Ultimate Solution for Finding Suitable Chiral Chromatographic Systems?

S Sagrado, C Pardo-Cortina… - Analytical …, 2024 - ACS Publications
The selection of suitable combinations of chiral stationary phases (CSPs) and mobile
phases (MPs) for the enantioresolution of chiral compounds is a complex issue that often …

Chiral separation of pharmaceuticals by high performance liquid chromatography

Y Zhang, S Yao, H Zeng, H Song - Current Pharmaceutical …, 2010 - ingentaconnect.com
The increasing demand for enantiopure drugs has led to the development of a variety of
stereoselective separation technologies. Among them, high performance liquid …

Molecular descriptor subset selection in theoretical peptide quantitative structure–retention relationship model development using nature-inspired optimization …

P Zuvela, JJ Liu, K Macur, T Baczek - Analytical chemistry, 2015 - ACS Publications
In this work, performance of five nature-inspired optimization algorithms, genetic algorithm
(GA), particle swarm optimization (PSO), artificial bee colony (ABC), firefly algorithm (FA) …

Artificial neural network modelling of the results of tympanoplasty in chronic suppurative otitis media patients

J Szaleniec, M Wiatr, M Szaleniec, J Składzień… - Computers in biology …, 2013 - Elsevier
The application of computer modelling for medical purposes, although challenging, is a
promising pathway for further development in the medical sciences. We present predictive …

LC/MS based tools and strategies on qualitative and quantitative analysis of herbal components in complex matrixes

L Wu, H Hao, G Wang - Current Drug Metabolism, 2012 - ingentaconnect.com
Accompanying with hot discussions on developing multi-target drugs for the therapy of multi-
gene diseases, herbal medicines are receiving more and more attention worldwide in both …

Asymmetric reduction of ketones and β-keto esters by (S)-1-phenylethanol dehydrogenase from denitrifying bacterium Aromatoleum aromaticum

A Dudzik, W Snoch, P Borowiecki… - Applied microbiology …, 2015 - Springer
Enzyme-catalyzed enantioselective reductions of ketones and keto esters have become
popular for the production of homochiral building blocks which are valuable synthons for the …

Mechanistic basis for the enantioselectivity of the anaerobic hydroxylation of alkylaromatic compounds by ethylbenzene dehydrogenase

M Szaleniec, A Dudzik, B Kozik, T Borowski… - Journal of Inorganic …, 2014 - Elsevier
The enantioselectivity of reactions catalyzed by ethylbenzene dehydrogenase, a
molybdenum enzyme that catalyzes the oxygen-independent hydroxylation of many …