Autograft replaced by a nerve guidance conduit (NGC) is challenging in peripheral nerve
injury because current NGC is still limited by precise conductivity and excellent …

Introduction Peripheral nerve injuries have been associated with increased healthcare costs
and decreased patients' quality of life. Aging represents one factor that slows the speed of …

Critical-sized bone defects remain an unsolved challenge because of the failure to induce
early reconstruction of the neuro-vascularization network. Nerve and vascular regeneration …

Peripheral nerve injury (PNI) is a major clinical problem that may lead to different levels of
sensory and motor dysfunction including paralysis. Due to the high disability rate and …

Schwann cells (SCs) have a critical role in the peripheral nervous system. These cells are
able to support axons during homeostasis and after injury. However, mutations in genes …

Preventing neuronal death after ischemic stroke (IS) is crucial for neuroprotective treatment,
yet current management options are limited. Enriched environment (EE) is an effective …

Axons are processes of neurons, up to a metre long, that form the essential biological cables
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …

Like the seasons of the year, all natural things happen in stages, going through adaptations
when challenged, and Schwann cells are a great example of that. During maturation, these …

Wallerian degeneration after peripheral nerve injury (PNI), that is, the autonomous
degeneration of distal axons, leads to an imbalance of iron homeostasis and easily induces …

Recent decades clearly demonstrate the growing use of nanomaterials in medical practice,
and their effectiveness is systematically confirmed by the consequent scientific research. An …