Metabolomics is the comprehensive study of small-molecule metabolites. Obtaining a wide
coverage of the metabolome is challenging because of the broad range of physicochemical …

Supercritical fluid chromatography (SFC), which employs pressurized carbon dioxide as the
major component of the mobile phase, has been known for several decades but has faced a …

For quite of time, supercritical fluid chromatography (SFC) is expected to make a big
revolution in separation technologies. The technique is well known for developing fast and …

The pharmaceutical industry is one of the most regulated industries worldwide, since the
drug products have to be safe and effective. The levels of impurities and degradation …

Supercritical fluid chromatography (SFC) is known since the early 1960's and it has gone
through several ups and downs during the past 50 years. The most remarkable rebirth came …

Lipidomics, the mass spectrometry-based comprehensive analysis of lipids, has attracted
attention as an analytical approach to provide novel insight into lipid metabolism and to …

Recent developments in supercritical fluid chromatography (SFC) have highlighted the
applicability of this technique for the analysis of highly polar compounds. The combination of …

Similarly to other hyphenated techniques, supercritical fluid chromatography (SFC) highly
benefits from the coupling with mass spectrometry (MS) detection as evident from the …

Sample preparation based on extraction techniques plays a crucial role in the entire
analytical process, as it ensures accurate and reliable analysis of analytes by eliminating …

Supercritical fluid chromatography (SFC) has recently experienced renovated impulse from
research groups. Its hyphenation to mass spectrometers (MS) proved to be of significant …