The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …

ABSTRACT Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that
can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants …

Pathogen interference is the ability of one pathogen to alter the course and clinical
outcomes of infection by another. With up to 3000 species of human pathogens the potential …

Background Viral infections of the respiratory tract represent a major global health concern.
Co-infection with bacteria may contribute to severe disease and increased mortality in …

Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and
the elderly. Here, using cryogenic electron microscopy and tomography combined with …

Background: With the advancement of diagnostic methods, a viral infection is increasingly
recognized in adult patients with pneumonia and the outcomes can be fatal especially in …

Pneumonia severity index (PSI) is an important scoring system that can assess the severity
of community acquired pneumonia and determine admission status. However, there is a lack …

Respiratory syncytial virus (RSV) infection is increasingly recognized as a cause of
significant morbidity and mortality in adults. We aimed to estimate the rates of age-specific …

Abstract Background Predictors of Respiratory Syncytial Virus (RSV) infection and
determinants of RSV unfavorable outcomes are still unclear. We assessed RSV burden and …

Background Shared and divergent predictors of clinical severity across respiratory viruses
may support clinical and community responses in the context of a novel respiratory …