The critical role of growth factors in gastric ulcer healing: the cellular and molecular mechanisms and potential clinical implications

AS Tarnawski, A Ahluwalia - Cells, 2021 - mdpi.com
In this article we review the cellular and molecular mechanisms of gastric ulcer healing. A
gastric ulcer (GU) is a deep defect in the gastric wall penetrating through the entire mucosa …

Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus

JM Miano, X Long, K Fujiwara - American Journal of …, 2007 - journals.physiology.org
Serum response factor (SRF) is a highly conserved and widely expressed, single copy
transcription factor that theoretically binds up to 1,216 permutations of a 10-base pair cis …

Cellular and molecular mechanisms of gastrointestinal ulcer healing

AS Tarnawski - Digestive diseases and sciences, 2005 - Springer
This paper reviews cellular and molecular mechanisms of gastrointestinal ulcer healing.
Ulcer healing, a genetically programmed repair process, includes inflammation, cell …

An overview of acetic acid ulcer models—the history and state of the art of peptic ulcer research—

S Okabe, K Amagase - Biological and Pharmaceutical Bulletin, 2005 - jstage.jst.go.jp
Four types of experimental chronic ulcer models, named acetic acid ulcer models, have
been developed to examine the healing process of peptic ulcers, screen anti-ulcer drugs …

Molecular mechanisms of epithelial regeneration and neovascularization during healing of gastric and esophageal ulcers

A S. Tarnawski, A Ahluwalia - Current medicinal chemistry, 2012 - benthamdirect.com
In this paper we reviewed and updated current views on the cellular and molecular
mechanisms of gastric and esophageal ulcer healing. Gastric ulcer healing encompasses …

[HTML][HTML] Role of serum response factor in the pathogenesis of disease

JM Miano - Laboratory investigation, 2010 - Elsevier
Serum response factor (SRF) is a ubiquitously expressed transcription factor that binds to a
DNA cis element known as the CArG box, which is found in the proximal regulatory regions …

[HTML][HTML] TRPV6 mediates capsaicin-induced apoptosis in gastric cancer cells—Mechanisms behind a possible new “hot” cancer treatment

J Chow, M Norng, J Zhang, J Chai - Biochimica et Biophysica Acta (BBA) …, 2007 - Elsevier
Capsaicin is an organic compound in chili peppers which are consumed by over one quarter
of the world's population daily. Studies have shown that capsaicin can induce apoptosis in …

Pathophysiology of gastric ulcer development and healing: molecular mechanisms and novel therapeutic options

M Fornai, L Antonioli, R Colucci, M Tuccori… - Peptic ulcer …, 2011 - books.google.com
The stomach plays a pivotal role in the digestion of foods that we eat. With the exception of
rare cases, this organ can resist to a large variety of noxious factors, including hydrochloric …

Neuroprotective effect of Ruminococcus albus on oxidatively stressed SH-SY5Y cells and animals

J Park, J Lee, Z Yeom, D Heo, YH Lim - Scientific reports, 2017 - nature.com
Recent evidence shows that the gut microbiota has an important role in gut-brain crosstalk
and is linked to neuronal disorders. The aim of this study was to investigate the effects of …

[HTML][HTML] Gut homeostasis, injury, and healing: New therapeutic targets

S Oncel, MD Basson - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
The integrity of the gastrointestinal mucosa plays a crucial role in gut homeostasis, which
depends upon the balance between mucosal injury by destructive factors and healing via …