Diagnosis, risk stratification, and response evaluation in classical myeloproliferative neoplasms

E Rumi, M Cazzola - Blood, The Journal of the American …, 2017 - ashpublications.org
Philadelphia-negative classical myeloproliferative neoplasms (MPNs) include polycythemia
vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). The 2016 …

Myeloproliferative neoplasms: a contemporary review

A Tefferi, A Pardanani - JAMA oncology, 2015 - jamanetwork.com
Polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF)
constitute theBCR-ABL1–negative myeloproliferative neoplasms and are characterized by …

[HTML][HTML] Classification and personalized prognosis in myeloproliferative neoplasms

J Grinfeld, J Nangalia, EJ Baxter… - … England Journal of …, 2018 - Mass Medical Soc
Background Myeloproliferative neoplasms, such as polycythemia vera, essential
thrombocythemia, and myelofibrosis, are chronic hematologic cancers with varied …

[HTML][HTML] Somatic mutations of calreticulin in myeloproliferative neoplasms

T Klampfl, H Gisslinger, AS Harutyunyan… - … England Journal of …, 2013 - Mass Medical Soc
Background Approximately 50 to 60% of patients with essential thrombocythemia or primary
myelofibrosis carry a mutation in the Janus kinase 2 gene (JAK2), and an additional 5 to …

Mutation‐enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera

A Tefferi, P Guglielmelli, TL Lasho… - British journal of …, 2020 - Wiley Online Library
Survival prediction in essential thrombocythaemia (ET) and polycythaemia vera (PV) is
currently based on clinically‐derived variables; we examined the possibility of integrating …

Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study

A Tefferi, E Rumi, G Finazzi, H Gisslinger… - Leukemia, 2013 - nature.com
Under the auspices of an International Working Group, seven centers submitted diagnostic
and follow-up information on 1545 patients with World Health Organization-defined …

JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes

E Rumi, D Pietra, V Ferretti, T Klampfl… - Blood, The Journal …, 2014 - ashpublications.org
Patients with essential thrombocythemia may carry JAK2 (V617F), an MPL substitution, or a
calreticulin gene (CALR) mutation. We studied biologic and clinical features of essential …

Targeted deep sequencing in polycythemia vera and essential thrombocythemia

A Tefferi, TL Lasho, P Guglielmelli, CM Finke… - Blood …, 2016 - ashpublications.org
Polycythemia vera (PV) is characterized by JAK2 and essential thrombocythemia (ET) by
JAK2, calreticulin (CALR), and myeloproliferative leukemia virus oncogene (MPL) mutations; …

Polycythemia vera and essential thrombocythemia: 2017 update on diagnosis, risk‐stratification, and management

A Tefferi, T Barbui - American journal of hematology, 2017 - Wiley Online Library
Abstract Disease overview Polycythemia Vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms respectively characterized by erythrocytosis and …

Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk‐stratification and management

A Tefferi, T Barbui - American journal of hematology, 2020 - Wiley Online Library
Disease overview Polycythemia vera (PV) and essential thrombocythemia (ET) are
myeloproliferative neoplasms (MPN) respectively characterized by clonal erythrocytosis and …