The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …

Publisher Summary This chapter considers two aspects of alpha-herpesvirus pathogenesis:
the invasion and spread of two representative viruses, herpes simplex virus (HSV) and …

Both observational and perturbational technologies are essential for advancing the
understanding of brain function and dysfunction. But while observational techniques have …

Memories are thought to be sparsely encoded in neuronal networks, but little is known about
why a given neuron is recruited or allocated to a particular memory trace. Previous research …

Abstract Development of methods that allow an efficient expression of exogenous genes in
animals would provide tools for gene function studies, treatment of diseases and for …

The concept behind gene therapy is simple—by delivering corrective genetic material to the
cells of a patient the symptoms of disease can be alleviated. But seven years after the first …

Remodeling of cortical connectivity is thought to allow initially hippocampus-dependent
memories to be expressed independently of the hippocampus at remote time points …

Diabetic cystopathy is a well-recognized complication of diabetes mellitus, which usually
develops in middle-aged or elderly patients with long-standing and poorly controlled …

Virus infection induces an antiviral response that is predominantly associated with the
synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type …

Repeated administration of morphine sensitizes animals to the stimulant and rewarding
properties of the drug. It also selectively increases expression of GluR1 (an AMPA glutamate …