Neurodegenerative disorders affect fifteen percent of the world's population and pose a
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …

Methods and results: Novel work with biological clock genes that oversee circadian rhythm
may meet this critical need by focusing upon the pathways of the mechanistic target of …

Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …

Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Prescribing a ketogenic diet (KD) is a century-old dietary intervention mainly used in the
context of intractable epilepsy. The classic KD and its variants regained popularity in recent …

As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

Iron metabolism in the body is a critical process for sustaining life as well as determining cell
fate [1-4]. As an essential element, iron in the ferrous state (Fe2+) is an electron donor but in …

Forkhead box O3a (FOXO3a) transcription factor, the most important member of Forkhead
box O family, is closely related to cell proliferation, apoptosis, autophagy, oxidative stress …

Demyelinating disorders affect a large proportion of the world's population. Multiple sclerosis
(MS) is a severe demyelinating disease that may impact both the body's immune system as …

Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease of
the central nervous system and it is understandable that environmental and genetic factors …