[HTML][HTML] Exercise and gait/movement analyses in treatment and diagnosis of Parkinson's Disease

J Burtscher, EM Moraud, D Malatesta, GP Millet… - Ageing Research …, 2024 - Elsevier
Cardinal motor symptoms in Parkinson's disease (PD) include bradykinesia, rest tremor
and/or rigidity. This symptomatology can additionally encompass abnormal gait, balance …

MRI biomarkers of freezing of gait development in Parkinson's disease

E Sarasso, S Basaia, C Cividini, T Stojkovic… - npj Parkinson's …, 2022 - nature.com
This study investigated longitudinal clinical, structural and functional brain alterations in
Parkinson's disease patients with freezing of gait (PD-FoG) and in those developing (PD …

New Insights into Freezing of Gait in Parkinson's Disease from Spectral Dynamic Causal Modeling

S Taniguchi, Y Kajiyama, T Kochiyama… - Movement …, 2024 - Wiley Online Library
Background Freezing of gait is one of the most disturbing motor symptoms of Parkinson's
disease (PD). However, the effective connectivity between key brain hubs that are …

Brain modulation after exergaming training in advanced forms of Parkinson's disease: a randomized controlled study

A Skrzatek, D Nuic, S Cherif, B Beranger… - Journal of …, 2024 - Springer
Background Physical activity combined with virtual reality and exergaming has emerged as
a new technique to improve engagement and provide clinical benefit for gait and balance …

[HTML][HTML] Developing a novel dual-injection FDG-PET imaging methodology to study the functional neuroanatomy of gait

HP Sigurdsson, L Alcock, M Firbank, R Wilson… - NeuroImage, 2024 - Elsevier
Gait is an excellent indicator of physical, emotional, and mental health. Previous studies
have shown that gait impairments in ageing are common, but the neural basis of these …

Safety and tolerability of adjunct non-invasive vagus nerve stimulation in people with parkinson's: a study protocol

HP Sigurdsson, H Hunter, L Alcock, R Wilson, I Pienaar… - BMC neurology, 2023 - Springer
Background Parkinson's disease (PD) is the fastest growing neurological condition
worldwide. Recent theories suggest that symptoms of PD may arise due to spread of Lewy …

Individual‐specific metabolic network based on 18F‐FDG PET revealing multi‐level aberrant metabolisms in Parkinson's disease

W Lu, T Song, J Li, Y Zhang, J Lu - Human Brain Mapping, 2024 - Wiley Online Library
Metabolic network analysis in Parkinson's disease (PD) based on 18F‐FDG PET has
revealed PD‐related metabolic patterns. However, alterations at the systemic metabolic …

Association of Striatal Dopamine Depletion and Brain Metabolism Changes With Motor and Cognitive Deficits in Patients With Parkinson Disease

HS Yoo, HK Kim, HK Na, S Kang, M Park, SJ Ahn… - Neurology, 2024 - neurology.org
Background and Objectives Parkinson disease (PD) shows degeneration of dopaminergic
neurons in the substantia nigra and characteristic changes in brain metabolism. However …

Resting‐state functional connectivity of the occipital cortex in different subtypes of Parkinson's disease

Y Lan, H Yuan, X Ma, CY Yin, X Liu… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims To examine whether functional connectivity (FC) of the occipital gyrus differs between
patients with Parkinson's disease (PD) motor subtypes and healthy controls (HCs). Methods …

Individual metabolic brain network abnormalities associated with drug-resistant mTLE vary in surgical outcomes

X Wang, P Zhang, D Lin, C Zhao, Z Huang… - Frontiers in …, 2024 - frontiersin.org
Objective This investigation aimed to elucidate alterations in metabolic brain network
connectivity in drug-resistant mesial temporal lobe epilepsy (DR-MTLE) patients, relating …