Bitter and astringent substances in green tea: Composition, human perception mechanisms, evaluation methods and factors influencing their formation

S Deng, G Zhang, OO Aluko, Z Mo, J Mao… - Food Research …, 2022 - Elsevier
Green tea is popularly known for its pleasant flavor and health-care functions. Bitterness and
astringency are the two important quality attributes of green tea that enrich tea flavor …

An overview of bitter compounds in foodstuffs: Classifications, evaluation methods for sensory contribution, separation and identification techniques, and mechanism …

J Yan, H Tong - Comprehensive reviews in food science and …, 2023 - Wiley Online Library
The bitter taste is generally considered an undesirable sensory attribute. However, bitter‐
tasting compounds can significantly affect the overall flavor of many foods and beverages …

BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides

P Charoenkwan, C Nantasenamat, MM Hasan… - …, 2021 - academic.oup.com
Motivation The identification of bitter peptides through experimental approaches is an
expensive and time-consuming endeavor. Due to the huge number of newly available …

BitterDB: taste ligands and receptors database in 2019

A Dagan-Wiener, A Di Pizio, I Nissim… - Nucleic Acids …, 2019 - academic.oup.com
Abstract BitterDB (http://bitterdb. agri. huji. ac. il) was introduced in 2012 as a central
resource for information on bitter-tasting molecules and their receptors. The information in …

Conserved sites and recognition mechanisms of T1R1 and T2R14 receptors revealed by ensemble docking and molecular descriptors and fingerprints combined with …

Z Cui, N Zhang, T Zhou, X Zhou, H Meng… - Journal of Agricultural …, 2023 - ACS Publications
Taste peptides, as an important component of protein-rich foodstuffs, potentiate the nutrition
and taste of food. Thereinto, umami-and bitter-taste peptides have been ex tensively …

[HTML][HTML] iBitter-SCM: Identification and characterization of bitter peptides using a scoring card method with propensity scores of dipeptides

P Charoenkwan, J Yana, N Schaduangrat… - Genomics, 2020 - Elsevier
In general, hydrolyzed proteins, plant-derived alkaloids and toxins displays unpleasant bitter
taste. Thus, the perception of bitter taste plays a crucial role in protecting animals from …

Bitter or not? BitterPredict, a tool for predicting taste from chemical structure

A Dagan-Wiener, I Nissim, N Ben Abu, G Borgonovo… - Scientific Reports, 2017 - nature.com
Bitter taste is an innately aversive taste modality that is considered to protect animals from
consuming toxic compounds. Yet, bitterness is not always noxious and some bitter …

Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling

JR Freund, CJ Mansfield, LJ Doghramji… - Journal of Biological …, 2018 - ASBMB
Bitter taste receptors (taste family 2 bitter receptor proteins; T2Rs), discovered in many
tissues outside the tongue, have recently become potential therapeutic targets. We have …

Classification-based machine learning approaches to predict the taste of molecules: A review

C Rojas, D Ballabio, V Consonni… - Food Research …, 2023 - Elsevier
The capacity to discriminate safe from dangerous compounds has played an important role
in the evolution of species, including human beings. Highly evolved senses such as taste …

Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor

BM Hariri, DB McMahon, B Chen, JR Freund… - Journal of Biological …, 2017 - ASBMB
Chronic rhinosinusitis has a significant impact on patient quality of life, creates billions of
dollars of annual healthcare costs, and accounts for∼ 20% of adult antibiotic prescriptions in …