The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients

YI Elshimali, H Khaddour, M Sarkissyan, Y Wu… - International journal of …, 2013 - mdpi.com
Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for
the management of malignant and benign neoplasms. Detecting circulating DNA in cancer …

Cell death and DAMPs in acute pancreatitis

R Kang, MT Lotze, HJ Zeh, TR Billiar, D Tang - Molecular medicine, 2014 - Springer
Cell death and inflammation are key pathologic responses of acute pancreatitis (AP), the
leading cause of hospital admissions for gastrointestinal disorders. It is becoming …

Laboratory diagnosis of acute pancreatitis: in search of the Holy Grail

G Lippi, M Valentino, G Cervellin - Critical reviews in clinical …, 2012 - Taylor & Francis
Acute pancreatitis is an acute inflammatory condition of the pancreas, which might extend to
local and distant extrapancreatic tissues. The global incidence varies between 17.5 and …

Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)

X Liu, J Ren, N Luo, H Guo, Y Zheng, J Li, F Tang… - Clinical …, 2019 - Springer
Background Comprehensive analysis of the tissue of origin of plasma cell-free DNA (cfDNA)
remains insufficient. A genome-scale DNA methylation method for this analysis is of both …

Is the role of circulating DNA as a biomarker of cancer being prematurely overrated?

M Van der Vaart, PJ Pretorius - Clinical biochemistry, 2010 - Elsevier
BACKGROUND: Circulating DNA is utilized widely as a genetic biomarker in a variety of
pathological conditions, mainly in cancerous conditions. Quantification of circulating DNA …

[HTML][HTML] The significance of liquid biopsy in pancreatic cancer

ZH Qi, HX Xu, SR Zhang, JZ Xu, S Li, HL Gao… - Journal of …, 2018 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer. The 5-
year survival rate for PDAC remains low because it is always diagnosed at an advanced …

Damage associated molecular patterns and neutrophil extracellular traps in acute pancreatitis

X Zhou, S Jin, J Pan, Q Lin, S Yang… - Frontiers in Cellular …, 2022 - frontiersin.org
Previous researches have emphasized a trypsin-centered theory of acute pancreatitis (AP)
for more than a century. With additional studies into the pathogenesis of AP, new …

Free DNA–new potential analyte in clinical laboratory diagnostics?

J Wagner - Biochemia medica, 2012 - hrcak.srce.hr
Sažetak The existence of cell free DNA in the human circulatory system has been known
since the 1950s, however, intensive research in this area has been conducted for the last …

[HTML][HTML] Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer

P Adamo, CM Cowley, CP Neal, V Mistry, K Page… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The majority of pancreatic ductal adenocarcinomas (PDAC) are diagnosed late so that
surgery is rarely curative. Earlier detection could significantly increase the likelihood of …

Cell-free plasma DNA and purine nucleotide degradation markers following weightlifting exercise

J Atamaniuk, C Vidotto, M Kinzlbauer, N Bachl… - European journal of …, 2010 - Springer
The present study aimed to investigate the acute effects of a single bout of high-intensive
strength training on the production of cell-free plasma DNA (cf-DNA), as well as on the …