Rifampicin was discovered in 1965 and remains one of the most important drugs in
tuberculosis treatment that is valued for its sterilizing activity and ability to shorten treatment …

ABSTRACT Introduction: The treatment of Mycobacterium abscessus lung disease faces
significant challenges due to intrinsic antibiotic resistance. New drugs are needed to cure …

Lung infections caused by Mycobacterium abscessus are emerging as a global threat to
individuals with cystic fibrosis and to other patient groups. Recent evidence for human-to …

Rationale: The management of macrolide-resistant Mycobacterium avium complex (MR-
MAC) pulmonary disease is difficult and is thought to be analogous to that of multidrug …

Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis (Mtb)
and is a major cause of morbidity and mortality. Successful treatment requires strict …

An excellent electrochemical sensor for determining rifabutin (RFB) by square-wave
voltammetry was developed utilizing a non-modified boron-doped diamond electrode …

Rifabutin is a spiro-piperidyl-rifamycin structurally closely related to rifampicin that shares
many of its properties. We attempted to address the reasons why this drug, which was …

Covering: 2011 to 2021 Structural division of natural naphthalenoid ansamycins, regarding
the type of the core and length of the ansa chain, and their biosynthetic pathways in …

Abstract β-glucan particles (GP) are polymeric carbohydrates, mainly found as components
of cell wall fungi, yeast, bacteria and also in cereals such as barley and oat, and have been …

Cross-resistance in rifamycins has been observed in rifampin (RIF)-resistant Mycobacterium
tuberculosis complex isolates; some rpoB mutations do not confer broad in vitro rifamycin …