Spheroids in cancer research: Recent advances and opportunities
In recent years, three-dimensional (3D) spheroid technology has emerged as a crucial
instrument in the realm of cancer research, offering a near-physiological model for probing …
instrument in the realm of cancer research, offering a near-physiological model for probing …
Beyond 2D: Novel biomaterial approaches for modeling the placenta
This review considers fully three-dimensional biomaterial environments of varying
complexity as these pertain to research on the placenta. The developments in placental cell …
complexity as these pertain to research on the placenta. The developments in placental cell …
Directed biomechanical compressive forces enhance fusion efficiency in model placental trophoblast cultures
PK Parameshwar, C Li, K Arnauts, J Jiang… - Scientific Reports, 2024 - nature.com
The syncytiotrophoblast is a multinucleated structure that arises from fusion of
mononucleated cytotrophoblasts, to sheath the placental villi and regulate transport across …
mononucleated cytotrophoblasts, to sheath the placental villi and regulate transport across …
Human placental organoids as a model to probe early gestation maternal immune dynamics
During pregnancy, the human placenta establishes tolerance toward fetal allogeneic tissue,
where specialized trophoblast subtypes play a complex role in local and peripheral …
where specialized trophoblast subtypes play a complex role in local and peripheral …
Engineered 3D Hydrogel Matrices to Modulate Trophoblast Stem Cell-Derived Placental Organoid Phenotype
Placental organoid models are a promising platform to study human placental development
and function. Organoid systems typically use naturally derived hydrogel extracellular …
and function. Organoid systems typically use naturally derived hydrogel extracellular …