The glymphatic system: Current understanding and modeling
We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
Cerebrospinal fluid flow
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …
through the brain transports not only those water-like fluids but also any solutes they carry …
Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS
The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …
whose composition changes as a function of an animal's physiological state. Ciliated …
Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development
Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation,
such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms …
such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms …
Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Cerebrospinal fluid (CSF) flowing through periarterial spaces is integral to the brain's
mechanism for clearing metabolic waste products. Experiments that track tracer particles …
mechanism for clearing metabolic waste products. Experiments that track tracer particles …
Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model
The movement of fluid into, through, and out of the brain plays an important role in clearing
metabolic waste. However, there is controversy regarding the mechanisms driving fluid …
metabolic waste. However, there is controversy regarding the mechanisms driving fluid …
Effects of increased intracranial pressure on cerebrospinal fluid influx, cerebral vascular hemodynamic indexes, and cerebrospinal fluid lymphatic efflux
T Xiang, D Feng, X Zhang, Y Chen… - Journal of Cerebral …, 2022 - journals.sagepub.com
The glymphatic-lymphatic fluid transport system (GLFTS) consists of glymphatic pathway
and cerebrospinal fluid (CSF) lymphatic outflow routes, allowing biological liquids from the …
and cerebrospinal fluid (CSF) lymphatic outflow routes, allowing biological liquids from the …
The mechanisms behind perivascular fluid flow
Flow of cerebrospinal fluid (CSF) in perivascular spaces (PVS) is one of the key concepts
involved in theories concerning clearance from the brain. Experimental studies have …
involved in theories concerning clearance from the brain. Experimental studies have …
Non-invasive enhancement of intracortical solute clearance using transcranial focused ultrasound
Transport of interstitial fluid and solutes plays a critical role in clearing metabolic waste from
the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote …
the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote …
Acute systemic LPS-exposure impairs perivascular CSF distribution in mice
Background The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital
for waste clearance in the brain. The sleep-dependent glymphatic system, which is …
for waste clearance in the brain. The sleep-dependent glymphatic system, which is …