[HTML][HTML] Imaging drug delivery to the lungs: Methods and applications in oncology
Direct delivery to the lung via inhalation is arguably one of the most logical approaches to
treat lung cancer using drugs. However, despite significant efforts and investment in this …
treat lung cancer using drugs. However, despite significant efforts and investment in this …
The unfulfilled promise of inhaled therapy in ventilator-associated infections: where do we go from here?
LB Palmer, GC Smaldone - … of aerosol medicine and pulmonary drug …, 2022 - liebertpub.com
Respiratory infection is common in intubated/tracheotomized patients and systemic antibiotic
therapy is often unrewarding. In 1967, the difficulty in treating Gram-negative respiratory …
therapy is often unrewarding. In 1967, the difficulty in treating Gram-negative respiratory …
Continuous infusion aerosol delivery of prostacyclins during mechanical ventilation: challenges, limitations, and recent advances
M McPeck, GC Smaldone - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Critically ill mechanically ventilated patients routinely receive aerosol delivery of
epoprostenol by continuous infusion of the nebulizer by syringe pump. This procedure is 'off …
epoprostenol by continuous infusion of the nebulizer by syringe pump. This procedure is 'off …
Real-Time In Vitro Assessment of Aerosol Delivery During Mechanical Ventilation
Background: A new real-time method for assessing factors determining aerosol delivery is
described. Methods: A breath-enhanced jet nebulizer operated in a ventilator/heated …
described. Methods: A breath-enhanced jet nebulizer operated in a ventilator/heated …
The impact of nebulized epoprostenol and iloprost on hemoglobin oxygen affinity: an ex vivo experiment
S Woyke, N Mair, T Haller, M Ronzani… - … of Physiology-Lung …, 2022 - journals.physiology.org
Inhalational prostacyclins act as strong vasodilators, potentially improving oxygenation by
reducing shunt fraction and ventilation-perfusion mismatch. As prostacyclin receptors are …
reducing shunt fraction and ventilation-perfusion mismatch. As prostacyclin receptors are …
Multidrug Aerosol Delivery During Mechanical Ventilation
Background: In the critically ill, pulmonary vasodilators are often provided off label to
intubated patients using continuous nebulization. If additional aerosol therapies such as …
intubated patients using continuous nebulization. If additional aerosol therapies such as …