Store-operated calcium entry (SOCE) is a ubiquitous Ca 2+ entry pathway that is activated in
response to depletion of ER-Ca 2+ stores and critically controls the regulation of …

Potassium channels belong to the largest and the most diverse super-families of ion
channels. Among them, Ca 2+-activated K+ channels (KCa) comprise many members …

Perfluoroalkyl substances (PFAS) are widely used in various manufacturing processes.
Accumulation of these chemicals has adverse effects on human health, including …

Abstract Store-operated Ca 2+ entry (SOCE) is critical for Ca 2+ signaling in nonexcitable
cells; however, its role in the regulation of cardiomyocyte Ca 2+ homeostasis has only …

Loss of dopaminergic (DA) neurons leads to Parkinson's disease; however, the mechanism
(s) for the vulnerability of DA neurons is (are) not fully understood. We demonstrate that …

Macrophage plasticity is essential for innate immunity, but in-depth signaling mechanism (s)
regulating their functional phenotypes are ill-defined. Here we report that interferon (IFN) γ …

Both increases in the basal cytosolic calcium concentration ([Ca2+] cyt) and [Ca2+] cyt
transients play a major role in cell cycle progression, cell proliferation and division. Calcium …

Abstract Significance: Store-operated Ca2+ entry (SOCE) is a ubiquitous Ca2+ signaling
mechanism triggered by Ca2+ depletion of the endoplasmic reticulum (ER) and by a variety …

Ion channels are transmembrane structures that allow the passage of ions across cell
membranes such as the plasma membrane or the membranes of various organelles like the …

Stem cells hold indefinite self-renewable capability that can be differentiated into all desired
cell types. Based on their plasticity potential, they are divided into totipotent (morula stage …