Background: There is growing recognition and understanding of the entities that cause
interstitial lung disease (ILD) in infants. These entities are distinct from those that cause ILD …

This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

Background When the original definition of BOS was formulated in 1993, the working group
had several goals. The group aimed to provide a classification system for airway disease …

Rationale: The relationship between clinical phenotype of childhood primary ciliary
dyskinesia (PCD) and ultrastructural defects and genotype is poorly defined. Objectives: To …

Results: Male sex was significantly associated with higher birth weight, death or oxygen
dependency (72% vs. 61%, boys vs. girls), hospital stay (97 vs. 86 days), pulmonary …

The ratio between the number of males and females in a society is referred to as the gender
ratio. This ratio is not stable but instead shaped by biological, social, technological, cultural …

Rationale: Better understanding of evolution of lung function in infants with cystic fibrosis
(CF) and its association with pulmonary inflammation and infection is crucial in informing …

The purpose of this study was to evaluate spirometric lung function in normal children ages
3 to 6 yr. Spirometric measurements were obtained at nursery and daycare centers by …

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Background Long-term benefits of newborn screening (NBS) for cystic fibrosis (CF) have
been established with respect to nutritional status, but effects on pulmonary health remain …