Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease
S Calafate, G Özturan, N Thrupp, J Vanderlinden… - Nature …, 2023 - nature.com
Early Alzheimer's disease (AD) is associated with hippocampal hyperactivity and decreased
sleep quality. Here we show that homeostatic mechanisms transiently counteract the …
sleep quality. Here we show that homeostatic mechanisms transiently counteract the …
Hypothalamic MCH neurons: from feeding to cognitive control
Modern neuroscience is progressively elucidating that the classic view positing distinct brain
regions responsible for survival, emotion, and cognitive functions is outdated. The …
regions responsible for survival, emotion, and cognitive functions is outdated. The …
Exploratory Rearing Is Governed by Hypothalamic Melanin-Concentrating Hormone Neurons According to Locus Ceruleus
Information seeking, such as standing on tiptoes to look around in humans, is observed
across animals and helps survival. Its rodent analog—unsupported rearing on hind legs …
across animals and helps survival. Its rodent analog—unsupported rearing on hind legs …
Exploratory rearing is governed by hypothalamic MCH cells according to the locus coeruleus
Exploration is essential for survival because it allows animals to gather information about
their environment. Rearing is a classic exploratory behavior, during which an animal …
their environment. Rearing is a classic exploratory behavior, during which an animal …
Hypothalamic MCH Neurons: From Feeding to Cognitive Control
Modern neuroscience is progressively elucidating that the classic view positing distinct brain
regions responsible for survival, emotion, and cognitive functions is outdated. The …
regions responsible for survival, emotion, and cognitive functions is outdated. The …