Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Klotho has antiaging properties, and serum levels decrease with physiological aging and
aging-related diseases, such as hypertension, cardiovascular, and chronic kidney disease …

Aims Despite the effects of statins in reducing cardiovascular events and slowing
progression of coronary atherosclerosis, significant cardiovascular (CV) risk remains …

Omega-3 fatty acids serve as the substrate for the formation of a group of lipid mediators that
mediate the resolution of inflammation. The cardiovascular inflammatory response in …

Background: Aortic valve stenosis (AVS), which is the most common valvular heart disease,
causes a progressive narrowing of the aortic valve as a consequence of thickening and …

G protein–coupled receptor 120 (GPR120) has been shown to negatively regulate
inflammation and apoptosis, but its role in cerebral ischemic injury remains unclear. Using …

Abstract Omega‐3 fatty acids (ω‐3FAs) such as Docosahexaenoic acid (DHA) and
Eicosapentanoic acid (EPA), are active ingredient of fish oil, which have larger health …

Treatment with icosapent ethyl 4 g/day, a highly purified and stable ethyl ester of
eicosapentaenoic acid (EPA), demonstrated a significant reduction in atherosclerotic …

Aims Vascular calcification, a marker of increased cardiovascular risk, is an active process
orchestrated by smooth muscle cells. Observational studies indicate that omega-3 fatty acids …

Objective: Vascular calcification is a critical pathology associated with increased
cardiovascular event risk, but there are no Food and Drug Administration-approved …