Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. Countless CRC patients undergo disease progression. As …

Lactate, traditionally regarded as a metabolic waste product at the terminal of the glycolysis
process, has recently been found to have multifaceted functional roles in metabolism and …

NLRP3 inflammasome activation is a highly regulated process for controlling secretion of the
potent inflammatory cytokines IL-1β and IL-18 that are essential during bacterial infection …

Auranofin is an oral gold (I) compound, initially developed for the treatment of rheumatoid
arthritis. Currently, Auranofin is under investigation for oncological application within a drug …

There is close crosstalk between cancer metabolism and immunity. Cancer metabolism
regulation is a promising therapeutic target for cancer immunotherapy. Warburg effect is …

Osteoarthritis (OA) is an age-related chronic degenerative joint disease where the main
characteristics include progressive degeneration of cartilage, varying degrees of synovitis …

Endometriosis is the presence of endometrial tissue outside the uterine cavity usually in the
ovaries, fallopian tube, and pelvic cavity. It's a chronic enigmatic gynecological condition …

Cellular signaling pathways involved in the maintenance of the equilibrium between cell
proliferation and apoptosis have emerged as rational targets that can be exploited in the …

With technological advancements, radiotherapy (RT) has become an effective non-surgical
treatment for hepatocellular carcinoma (HCC), comprehensively improving the local control …

Metabolic disturbance, particularly of glucose metabolism, is a hallmark of tumors such as
non-small cell lung cancer (NSCLC). Cancer cells tend to reprogram a majority of glucose …