Novel syntheses of azetidines and azetidinones

A Brandi, S Cicchi, FM Cordero - Chemical Reviews, 2008 - ACS Publications
Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

Azomethine ylides in organic synthesis

C Najera, JM Sansano - Current Organic Chemistry, 2003 - benthamdirect.com
This review will attempt to cover the literatures published from 1988 dealing with cyclic and
acyclic azomethine ylides in which a part or the whole of the ylide conjugation is included in …

The chemistry of 2-aminocycloalkanecarboxylic acids

F Fülöp - Chemical Reviews, 2001 - ACS Publications
Although of less importance than their R-analogues, β-amino acids are also present in
peptides and different heterocycles, and their free forms and derivatives exhibit interesting …

The practice of ring constraint in peptidomimetics using bicyclic and polycyclic amino acids

S Hanessian, L Auzzas - Accounts of chemical research, 2008 - ACS Publications
Medicinal chemistry has witnessed major advances with the discovery of small synthetic
molecules that mimic natural peptidic substrates. These small synthetic mimics do not …

Entre information & processus de communication: l'intelligence territoriale

Y Bertacchini, L Oueslati - International Journal of Info & Com Sciences …, 2003 - hal.science
A l'origine physiques, les échelons territoriaux intègrent progressivement les TIC. Ces
dernières brouillent les découpages administratifs et favorisent l'émergence de territoires …

One-pot construction of diverse β-lactam scaffolds via the green oxidation of amines and its application to the diastereoselective synthesis of β-amino acids

Y Yamamoto, S Kodama, R Nishimura… - The Journal of …, 2021 - ACS Publications
In this study, a simple one-pot construction of β-lactam scaffolds was successfully achieved
via 4, 6-dihydroxysalicylic acid-catalyzed organocatalytic oxidation of amines to imines …

Synthesis of some novel indeno [1, 2-b] quinoxalin spiro-β-lactam conjugates

JA Rad, A Jarrahpour, CC Ersanlı, Z Atioğlu, M Akkurt… - Tetrahedron, 2017 - Elsevier
This article reports the synthesis of some new spiro-β-lactams bearing an indeno [1, 2-b]
quinoxaline ring system, prepared by a [2+ 2] cycloaddition of ketenes with imines derived …

Beta-lactams as inhibitors of serine enzymes

MI Konaklieva - CURRENT MEDICINAL CHEMISTRY ANTI …, 2002 - ingentaconnect.com
For nearly six decades, penicillins have been used widely to treat bacterial infections. The
development of multidrug resistance, however, has reduced the effectiveness of β-lactams …

Two-step stereocontrolled synthesis of densely functionalized cyclic β-aminoesters containing four stereocenters, based on a new cerium (IV) ammonium nitrate …

V Sridharan, JC Menendez - Organic Letters, 2008 - ACS Publications
The cerium (IV) ammonium nitrate (CAN)-catalyzed sequential, one-pot reaction between
alkylamines, β-ketoesters, and chalcones afforded cis-4, 6-disubstituted 2 …

Synthesis of novel Azol-β-lactam derivatives starting from phenyl piperazine and investigation of their antiurease activity and antioxidant capacity comparing with their …

A Mermer, H Bayrak, Y Şirin, M Emirik… - Journal of Molecular …, 2019 - Elsevier
This study reports the synthesis, biological investigation and molecular docking of novel β-
lactam derivatives bearing 1, 3, 4-thiadiazole and 1, 3, 4-oxadiazole ring system. The …