[HTML][HTML] HEART UK consensus statement on Lipoprotein (a): A call to action

J Cegla, RDG Neely, M France, G Ferns, CD Byrne… - Atherosclerosis, 2019 - Elsevier
Abstract Lipoprotein (a), Lp (a), is a modified atherogenic low-density lipoprotein particle that
contains apolipoprotein (a). Its levels are highly heritable and variable in the population …

Lipoprotein (a): a risk factor for atherosclerosis and an emerging therapeutic target

SA Di Fusco, M Arca, P Scicchitano, A Alonzo… - Heart, 2023 - heart.bmj.com
Lipoprotein (a)(Lp (a)) is a complex circulating lipoprotein, and increasing evidence has
demonstrated its role as a risk factor for atherosclerotic cardiovascular disease (ASCVD) …

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the management of dyslipidemia and …

Y Handelsman, PS Jellinger, CK Guerin… - Endocrine practice, 2020 - Elsevier
The treatment of lipid disorders begins with lifestyle therapy to improve nutrition, physical
activity, weight, and other factors that affect lipids. Secondary causes of lipid disorders …

[HTML][HTML] Review of serum biomarkers in carotid atherosclerosis

E Martinez, J Martorell, V Riambau - Journal of Vascular Surgery, 2020 - Elsevier
Background Carotid artery atherosclerotic stenosis is a preventable major cause of stroke,
but there is still a need for definition of high-risk plaque in asymptomatic patients who might …

Lipoprotein (a) the insurgent: a new insight into the structure, function, metabolism, pathogenicity, and medications affecting lipoprotein (a) molecule

MM Jawi, J Frohlich, SY Chan - Journal of lipids, 2020 - Wiley Online Library
Lipoprotein (a)[Lp (a)], aka “Lp little a”, was discovered in the 1960s in the lab of the
Norwegian physician Kåre Berg. Since then, we have greatly improved our knowledge of …

Treatment and prevention of lipoprotein (a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics

DI Swerdlow, DA Rider, A Yavari… - Cardiovascular …, 2022 - academic.oup.com
Lipid-and lipoprotein-modifying therapies have expanded substantially in the last 25 years,
resulting in reduction in the incidence of major adverse cardiovascular events. However, no …

Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …

Lipoprotein (a) and inflammation-pathophysiological links and clinical implications for cardiovascular disease

S Simantiris, AS Antonopoulos, C Papastamos… - Journal of Clinical …, 2023 - Elsevier
The role of lipoprotein (a)(Lp [a]) as a significant and possibly causal cardiovascular disease
(CVD) risk factor has been well established. Many studies, mostly experimental, have …

Novel therapeutical approaches to managing atherosclerotic risk

RV Giglio, A Pantea Stoian, K Al-Rasadi… - International Journal of …, 2021 - mdpi.com
Atherosclerosis is a multifactorial vascular disease that leads to inflammation and stiffening
of the arteries and decreases their elasticity due to the accumulation of calcium, small dense …

Lipoprotein (a): when to measure and how to treat?

D Rhainds, MR Brodeur, JC Tardif - Current Atherosclerosis Reports, 2021 - Springer
Abstract Purpose of Review The purpose of this article is to review current evidence for
lipoprotein (a)(Lp (a)) as a risk factor for multiple cardiovascular (CV) disease phenotypes …