Targeted delivery to tumors: multidirectional strategies to improve treatment efficiency

OM Kutova, EL Guryev, EA Sokolova, R Alzeibak… - Cancers, 2019 - mdpi.com
Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …

Applications of superparamagnetic iron oxide nanoparticles in drug and therapeutic delivery, and biotechnological advancements

M Suciu, CM Ionescu, A Ciorita… - Beilstein Journal of …, 2020 - beilstein-journals.org
Superparamagnetic iron oxide nanoparticles (SPIONs) have unique properties with regard
to biological and medical applications. SPIONs have been used in clinical settings although …

(Poly) cation-induced protection of conventional and wireframe DNA origami nanostructures

Y Ahmadi, E De Llano, I Barišić - Nanoscale, 2018 - pubs.rsc.org
DNA nanostructures hold immense potential to be used for biological and medical
applications. However, they are extremely vulnerable towards salt depletion and nucleases …

Generation of peptides using phage display technology for cancer diagnosis and molecular imaging

HS Pung, GJ Tye, CH Leow, WK Ng, NS Lai - Molecular Biology Reports, 2023 - Springer
Cancer is one of the leading causes of mortality worldwide; nearly 10 million people died
from it in 2020. The high mortality rate results from the lack of effective screening …

Theranostic nanoparticles for detection and treatment of pancreatic cancer

H Agarwal, RC Bynum, N Saleh… - Wiley …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is one of the most recalcitrant cancers due to its
late diagnosis, poor therapeutic response, and highly heterogeneous microenvironment …

Advances of nanoworms in diagnosis, treatment, and theranostics

K Borse, P Shende - Materials Advances, 2023 - pubs.rsc.org
Engineered nanoparticles offer potential applications in the biomedical field, such as drug
delivery and magnetic resonance imaging; however, they exhibit poor hemocompatibility …

Biomedical applications of fluorescent and magnetic resonance imaging dual‐modality probes

Y Deng, A Xu, Y Yu, C Fu, G Liang - ChemBioChem, 2019 - Wiley Online Library
Molecular imaging plays a critical role in biomedical research. The combination of different
modalities can generate complementary information and provide synergistic advantages …

Pancreatic cancer: Recent advances in nanoformulation-based therapies

P Desai, D Ann, J Wang… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Pancreatic cancer is the fourth leading cause of death in the United States and has a 5-year
life expectancy of~ 8%. Currently, only a few drugs have been approved by the United …

[HTML][HTML] DNA origami-enhanced binding of aptamers to Staphylococcus aureus cells

Y Ahmadi, TR Umrekar, N Mutter, M Beeby… - … and Bioelectronics: X, 2024 - Elsevier
The combination of DNA origami nanostructures and aptamers provides a powerful
technology for diagnostic assays. Here, we functionalized a DNA origami nanostructure with …

[HTML][HTML] Advancements of molecular imaging and radiomics in pancreatic carcinoma

XX Pang, L Xie, WJ Yao, XX Liu, B Pan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Despite the recent progress of medical technology in the diagnosis and treatment of tumors,
pancreatic carcinoma remains one of the most malignant tumors, with extremely poor …