One of the defining characteristics of the research of Ann E. Kelley was her recognition that
the neuroscience underlying basic learning and motivation processes also shed significant …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Humans eat for many reasons, including the rewarding qualities of foods. A host of
neurotransmitters have been shown to influence eating behavior and some of these appear …

Abstract Purpose of Review Eating behavior provides energy to ensure proper functioning of
the organism. Reward aids in seeking foods that bring energy and pleasant taste, whose …

Patients with irritable bowel syndrome (IBS) exhibit low-grade inflammation and increased
gut permeability. Dietary sugar has been shown to contribute to low-grade inflammation and …

Overconsumption of sugars contributes to poor health outcomes. Sugars are often added to
commercial foods and beverages in low concentrations and these hidden sugars are …

The notion that sweetness is 'addictive'endures in the scientific literature and in the popular
press. The most common targets of food cravings and addictions are energy‐dense foods …

Functional-anatomical changes in reward related brain circuits are described in chronic pain
patients who report anhedonia or depressed mood. In pre-clinical rodent models of …

Functional elucidation of the endogenous opioid system temporally paralleled the creation
and growth of the journal, Peptides, under the leadership of its founding editor, Dr. Abba …

Animal models allow us to investigate the basic mechanisms by which food intake is
regulated. There are a host of neuroregulators distributed across a complex central network …