Recent advances in biological nanopores for nanopore sequencing, sensing and comparison of functional variations in MspA mutants
H Bhatti, R Jawed, I Ali, K Iqbal, Y Han, Z Lu, Q Liu - Rsc Advances, 2021 - pubs.rsc.org
Biological nanopores are revolutionizing human health by the great myriad of detection and
diagnostic skills. Their nano-confined area and ingenious shape are suitable to investigate a …
diagnostic skills. Their nano-confined area and ingenious shape are suitable to investigate a …
Investigating the origins of the mutational signatures in cancer
Most of the risk factors associated with chronic and complex diseases, such as cancer, stem
from exogenous and endogenous exposures experienced throughout an individual's life …
from exogenous and endogenous exposures experienced throughout an individual's life …
Detection and discrimination of DNA adducts differing in size, regiochemistry, and functional group by nanopore sequencing
I Nookaew, P Jenjaroenpun, H Du… - Chemical research in …, 2020 - ACS Publications
Chemically induced DNA adducts can lead to mutations and cancer. Unfortunately, because
common analytical methods (eg, liquid chromatography-mass spectrometry) require adducts …
common analytical methods (eg, liquid chromatography-mass spectrometry) require adducts …
γ-Hemolysin nanopore is sensitive to guanine-to-inosine substitutions in double-stranded DNA at the single-molecule level
Biological nanopores provide a unique single-molecule sensing platform to detect target
molecules based on their specific electrical signatures. The γ-hemolysin (γ-HL) protein …
molecules based on their specific electrical signatures. The γ-hemolysin (γ-HL) protein …
Simultaneous Dual-Site Identification of 5mC/8oG in DNA Triplex Using a Nanopore Sensor
W Li, Y Wang, Y Xiao, M Li, Q Liu, L Liang… - … Applied Materials & …, 2022 - ACS Publications
DNA triplex participates in delivering site-specific epigenetic modifications critical for the
regulation of gene expression. Among these marks, 5mC with 8oG functions …
regulation of gene expression. Among these marks, 5mC with 8oG functions …
Current and future methodology for quantitation and site-specific mapping the location of DNA adducts
Formation of DNA adducts is a key event for a genotoxic mode of action, and their presence
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
[PDF][PDF] Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts. Toxics 2022, 10, 45
G Boysen, I Nookaew - 2022 - academia.edu
Formation of DNA adducts is a key event for a genotoxic mode of action, and their presence
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
Interrogation of A-Form Duplexes and Parallel G-Quadruplexes with Alpha-Hemolysin Mutants
ME Browning - 2021 - search.proquest.com
Nanopores have been used to study deoxyribonucleic acid (DNA) and ribonucleic acid
(RNA) at a single-molecule level. The most commonly used protein nanopore for these …
(RNA) at a single-molecule level. The most commonly used protein nanopore for these …