The mechanisms of vesicle budding and fusion
JS Bonifacino, BS Glick - cell, 2004 - cell.com
Genetic and biochemical analyses of the secretory pathway have produced a detailed
picture of the molecular mechanisms involved in selective cargo transport between …
picture of the molecular mechanisms involved in selective cargo transport between …
The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration
M Costanzo, C Zurzolo - Biochemical Journal, 2013 - portlandpress.com
The misfolding and aggregation of specific proteins is a common hallmark of many
neurodegenerative disorders, including highly prevalent illnesses such as Alzheimer's and …
neurodegenerative disorders, including highly prevalent illnesses such as Alzheimer's and …
Dynasore, a cell-permeable inhibitor of dynamin
Dynamin is essential for clathrin-dependent coated vesicle formation. It is required for
membrane budding at a late stage during the transition from a fully formed pit to a pinched …
membrane budding at a late stage during the transition from a fully formed pit to a pinched …
Tissue-specific alternative splicing remodels protein-protein interaction networks
Alternative splicing plays a key role in the expansion of proteomic and regulatory complexity,
yet the functions of the vast majority of differentially spliced exons are not known. In this …
yet the functions of the vast majority of differentially spliced exons are not known. In this …
Assembly-dependent endocytosis and clearance of extracellular a-synuclein
Abnormal folding and accumulation of α-synuclein is implicated in several neurological
disorders including Parkinson's disease. Although α-synuclein is a typical cytoplasmic …
disorders including Parkinson's disease. Although α-synuclein is a typical cytoplasmic …
Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins
Cell membranes undergo continuous curvature changes as a result of membrane trafficking
and cell motility. Deformations are achieved both by forces extrinsic to the membrane as well …
and cell motility. Deformations are achieved both by forces extrinsic to the membrane as well …
Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway
The mechanisms that order cellular packing geometry are critical for the functioning of many
tissues, but they are poorly understood. Here, we investigate this problem in the developing …
tissues, but they are poorly understood. Here, we investigate this problem in the developing …
Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis
E-cadherin plays a pivotal role in epithelial morphogenesis. It controls the intercellular
adhesion required for tissue cohesion and anchors the actomyosin-driven tension needed to …
adhesion required for tissue cohesion and anchors the actomyosin-driven tension needed to …
The division of endosymbiotic organelles
KW Osteryoung, J Nunnari - Science, 2003 - science.org
Mitochondria and chloroplasts are essential eukaryotic organelles of endosymbiotic origin.
Dynamic cellular machineries divide these organelles. The mechanisms by which …
Dynamic cellular machineries divide these organelles. The mechanisms by which …
AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling
Abstract RME-1/EHD1 (receptor mediated endocytosis/Eps15 homology-domain containing
1) family proteins are key residents of the recycling endosome, which are required for …
1) family proteins are key residents of the recycling endosome, which are required for …