Solid lipid nanoparticles and nanostructured lipid carriers in oral cancer drug delivery
S Nasirizadeh, B Malaekeh-Nikouei - Journal of Drug Delivery Science and …, 2020 - Elsevier
Most cancer disease can be treated by the parenteral anticancer delivery method. The
intravenous route takes the wholly bioavailable, accurate dose of the drug immediately to …
intravenous route takes the wholly bioavailable, accurate dose of the drug immediately to …
Next-generation materials for RNA–lipid nanoparticles: lyophilization and targeted transfection
T Wang, TC Sung, T Yu, HY Lin, YH Chen… - Journal of Materials …, 2023 - pubs.rsc.org
RNA, including mRNA, siRNA and miRNA, is part of a new class of patient treatments that
prevent and treat several diseases. As an alternative to DNA therapy using plasmid DNA …
prevent and treat several diseases. As an alternative to DNA therapy using plasmid DNA …
[HTML][HTML] Nanostructured lipid carriers for oral bioavailability enhancement of raloxifene: Design and in vivo study
The objective of present work was to utilize potential of nanostructured lipid carriers (NLCs)
for improvement in oral bioavailability of raloxifene hydrochloride (RLX). RLX loaded NLCs …
for improvement in oral bioavailability of raloxifene hydrochloride (RLX). RLX loaded NLCs …
Solid lipid nanoparticles (SLN) of Efavirenz as lymph targeting drug delivery system: Elucidation of mechanism of uptake using chylomicron flow blocking approach
V Makwana, R Jain, K Patel, M Nivsarkar… - International journal of …, 2015 - Elsevier
The aim of the present work was to develop a lymph targeted SLN formulation of
antiretroviral (ARV) drug and to have an understanding of its underlying mechanism of …
antiretroviral (ARV) drug and to have an understanding of its underlying mechanism of …
Candesartan cilexetil loaded solid lipid nanoparticles for oral delivery: characterization, pharmacokinetic and pharmacodynamic evaluation
N Dudhipala, K Veerabrahma - Drug delivery, 2016 - Taylor & Francis
Candesartan cilexetil (CC) is used in the treatment of hypertension and heart failure. It has
poor aqueous solubility and low oral bioavailability. In this work, CC loaded solid lipid …
poor aqueous solubility and low oral bioavailability. In this work, CC loaded solid lipid …
Folic acid receptor-targeted solid lipid nanoparticles to enhance cytotoxicity of letrozole through induction of caspase-3 dependent-apoptosis for breast cancer …
A Yassemi, S Kashanian, H Zhaleh - … development and technology, 2020 - Taylor & Francis
Chemotherapy using cytotoxic agents, such as letrozole (LTZ), is one of the most effective
treatments for hormone-dependent breast cancer. Nevertheless, nonspecific targeting of the …
treatments for hormone-dependent breast cancer. Nevertheless, nonspecific targeting of the …
Lipid nanoparticles for oral delivery of raloxifene: optimization, stability, in vivo evaluation and uptake mechanism
PR Ravi, N Aditya, H Kathuria, S Malekar… - European journal of …, 2014 - Elsevier
Raloxifene HCl (RLX) shows low oral bioavailability (< 2%) in humans due to poor aqueous
solubility and extensive (> 90%) metabolism in gut. Lipid nanoparticles (SLN) with glyceryl …
solubility and extensive (> 90%) metabolism in gut. Lipid nanoparticles (SLN) with glyceryl …
Luteolin-loaded solid lipid nanoparticles synthesis, characterization, & improvement of bioavailability, pharmacokinetics in vitro and vivo studies
H Dang, MHW Meng, H Zhao, J Iqbal, R Dai… - Journal of Nanoparticle …, 2014 - Springer
Abstract Luteolin (LU, 5, 7, 3′, 4′-tetrahydroxyflavone) most active compound in Chinese
herbal flavones has been acting as a antimicrobial, anti-inflammatory, anti-cancer, and …
herbal flavones has been acting as a antimicrobial, anti-inflammatory, anti-cancer, and …
Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation
N Dudhipala, K Veerabrahma - European Journal of Pharmaceutics and …, 2017 - Elsevier
The intent of this investigation was to improve pharmacokinetic (PK) and pharmacodynamic
(PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs). RC is anti …
(PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs). RC is anti …
Pharmacokinetic and pharmacodynamic studies of nisoldipine-loaded solid lipid nanoparticles developed by central composite design
N Dudhipala, K Veerabrahma - Drug development and industrial …, 2015 - Taylor & Francis
Objective: Nisoldipine (ND) is a potential antihypertensive drug with low oral bioavailability.
The aim was to develop an optimal formulation of ND-loaded solid lipid nanoparticles (ND …
The aim was to develop an optimal formulation of ND-loaded solid lipid nanoparticles (ND …