Adverse childhood experiences (ACEs) and substance use disorder (SUD): A scoping review
Background The long-term negative effects of adverse childhood experiences (ACEs) and
their impact on physical and mental health has been widely studied. However, research …
their impact on physical and mental health has been widely studied. However, research …
Neuroimaging impaired response inhibition and salience attribution in human drug addiction: a systematic review
The impaired response inhibition and salience attribution (iRISA) model proposes that
impaired response inhibition and salience attribution underlie drug seeking and taking. To …
impaired response inhibition and salience attribution underlie drug seeking and taking. To …
The neural basis of reversal learning: An updated perspective
Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …
and have been used as assays, across species, for altered cognitive processes in a host of …
Synaptic mechanisms underlying persistent cocaine craving
ME Wolf - Nature reviews neuroscience, 2016 - nature.com
Although it is challenging for individuals with cocaine addiction to achieve abstinence, the
greatest difficulty is avoiding relapse to drug taking, which is often triggered by cues …
greatest difficulty is avoiding relapse to drug taking, which is often triggered by cues …
Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making
A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
[HTML][HTML] Sufficiency of mesolimbic dopamine neuron stimulation for the progression to addiction
The factors causing the transition from recreational drug consumption to addiction remain
largely unknown. It has not been tested whether dopamine (DA) is sufficient to trigger this …
largely unknown. It has not been tested whether dopamine (DA) is sufficient to trigger this …
Cognitive impairments in alcohol-dependent subjects
F Bernardin, A Maheut-Bosser, F Paille - Frontiers in psychiatry, 2014 - frontiersin.org
Chronic excessive alcohol consumption induces cognitive impairments mainly affecting
executive functions, episodic memory, and visuospatial capacities related to multiple brain …
executive functions, episodic memory, and visuospatial capacities related to multiple brain …
The etiologic, theory-based, ontogenetic hierarchical framework of alcohol use disorder: A translational systematic review of reviews.
Abstract Modern nosologies (eg, International Classification of Diseases, 11th edition [ICD-
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …
Genome-wide association studies of impulsive personality traits (BIS-11 and UPPS-P) and drug experimentation in up to 22,861 adult research participants identify …
S Sanchez-Roige, P Fontanillas, SL Elson… - Journal of …, 2019 - Soc Neuroscience
Impulsive personality traits are complex heritable traits that are governed by frontal-
subcortical circuits and are associated with numerous neuropsychiatric disorders …
subcortical circuits and are associated with numerous neuropsychiatric disorders …
Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice
LM Reynolds, G Hernandez, D MacGowan… - Nature …, 2023 - nature.com
Initiating drug use during adolescence increases the risk of developing addiction or other
psychopathologies later in life, with long-term outcomes varying according to sex and exact …
psychopathologies later in life, with long-term outcomes varying according to sex and exact …