Natural bicyclic sesquiterpenes, β‐caryophyllene (BCP) and β‐caryophyllene oxide (BCPO),
are present in a large number of plants worldwide. Both BCP and BCPO (BCP (O)) possess …

Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Essential oils are complex mixtures isolated from aromatic plants which may possess
antioxidant and anti-inflammatory activities of interest in thye food and cosmetic industries as …

Essential oils (EOs) have risen in popularity over the past decade. These oils function in
society as holistic integrative modalities to traditional medicinal treatments, where many …

Background Medicinal cannabis registries typically report pain as the most common reason
for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and …

In the last few years more and more studies on the biological properties of essential oils
have been published and it seemed worthwhile to compile the studies of 2009, 2008 and the …

Background: β-Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in
essential oils from various spices, fruits and medicinal as well as ornamental plants. It is …

The cannabinoid type two receptors (CB2), an important component of the endocannabinoid
system, have recently emerged as neuromodulators and therapeutic targets for …

Osteoarthritis is a progressive joint disease and a major cause of disability for which no
curative therapies are yet available. To identify compounds with potential anti-osteoarthritic …