Characterization of thermostable carboxypeptidase from high-altitude hot spring metagenome
This study explored the metagenome of the Pir Panjal Hot Spring (PPHS) to identify
thermostable hydrolases. The carboxypeptidase (CarP) gene was successfully amplified …
thermostable hydrolases. The carboxypeptidase (CarP) gene was successfully amplified …
Design of a TSR-based project learning strategy for biochemistry undergraduate teaching and research labs: a case study
CR Reaux, SA Meche, JM Grider, S Dhanabal… - Frontiers in …, 2025 - frontiersin.org
Given the exponential growth of biochemical data and deep effect of computational methods
on life sciences, there is a need to rethink undergraduate curricula. A project-oriented …
on life sciences, there is a need to rethink undergraduate curricula. A project-oriented …
Introducing mirror-image discrimination capability to the TSR-based method for capturing stereo geometry and understanding hierarchical structure relationships of …
T Sarkar, Y Chen, Y Wang, Y Chen, F Chen… - … biology and chemistry, 2023 - Elsevier
We have developed a Triangular Spatial Relationship (TSR)-based computational method
for protein structure comparison and motif discovery that is both sequence and structure …
for protein structure comparison and motif discovery that is both sequence and structure …
Development of a novel representation of drug 3D structures and enhancement of the TSR-based method for probing drug and target interactions
TI Milon, Y Wang, RL Fontenot, P Khajouie… - … Biology and Chemistry, 2024 - Elsevier
Understanding the mechanisms underlying interactions between drugs and target proteins
is critical for drug discovery. In our earlier studies, we introduced the Triangular Spatial …
is critical for drug discovery. In our earlier studies, we introduced the Triangular Spatial …