Food as medicine: targeting the uraemic phenotype in chronic kidney disease

D Mafra, NA Borges, B Lindholm, PG Shiels… - Nature Reviews …, 2021 - nature.com
The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities

Z Huang, AH Rose, PR Hoffmann - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Dietary selenium (] Se), mainly through its incorporation into selenoproteins, plays
an important role in inflammation and immunity. Adequate levels of Se are important for …

[HTML][HTML] Diet and microbiota in inflammatory bowel disease: The gut in disharmony

DCM Rapozo, C Bernardazzi… - World journal of …, 2017 - ncbi.nlm.nih.gov
Bacterial colonization of the gut shapes both the local and the systemic immune response
and is implicated in the modulation of immunity in both healthy and disease states. Recently …

Selenium preserves mitochondrial function, stimulates mitochondrial biogenesis, and reduces infarct volume after focal cerebral ischemia

SL Mehta, S Kumari, N Mendelev, PA Li - BMC neuroscience, 2012 - Springer
Background Mitochondrial dysfunction is one of the major events responsible for activation
of neuronal cell death pathways during cerebral ischemia. Trace element selenium has …

Selenium and inflammatory bowel disease

AK Kudva, AE Shay, KS Prabhu - American Journal of …, 2015 - journals.physiology.org
Dietary intake of the micronutrient selenium is essential for normal immune functions.
Selenium is cotranslationally incorporated as the 21st amino acid, selenocysteine, into …

Selenium and its' role in the maintenance of genomic stability

LR Ferguson, N Karunasinghe, S Zhu… - … research/fundamental and …, 2012 - Elsevier
Selenium (Se) is an essential micronutrient for humans, acting as a component of the
unusual amino acids, selenocysteine (Se-Cys) and selenomethionine (Se-Met). Where Se …

The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: A randomized …

M Khazdouz, NE Daryani, M Cheraghpour… - European journal of …, 2023 - Springer
Abstract Purpose Selenium (Se) supplementation may help reduce inflammation and
disease activity in ulcerative colitis (UC) patients. We investigated the therapeutic effects of …

Roles for selenium and selenoprotein P in the development, progression, and prevention of intestinal disease

SP Short, JM Pilat, CS Williams - Free Radical Biology and Medicine, 2018 - Elsevier
Selenium (Se) is a micronutrient essential to human health, the function of which is mediated
in part by incorporation into a class of proteins known as selenoproteins (SePs). As many …

Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium

S Kumari, SL Mehta, PA Li - PloS one, 2012 - journals.plos.org
Glutamate-induced cytotoxicity is partially mediated by enhanced oxidative stress. The
objectives of the present study are to determine the effects of glutamate on mitochondrial …

Genetic variants in selenoprotein genes increase risk of colorectal cancer

C Méplan, DJ Hughes, B Pardini, A Naccarati… - …, 2010 - academic.oup.com
Low selenium (Se) status correlates with increased risk of colorectal cancer (CRC). Since Se
exerts its biological roles through the selenoproteins, genetic variations in selenoprotein …