Nitrile and amide-based products exhibit substantial influence within our societal framework,
manifesting extensive utilization. Commercial products such as Nitrile Butadiene Rubber …

Hundreds of neurotoxic insecticides are currently in use. However, only a few direct targets
have been identified. Here, using Drosophila and the insecticide flonicamid, we identified …

Inward rectifier K+ (Kir) channels have been studied extensively in mammals, where they
play critical roles in health and disease. In insects, Kir channels have recently been found to …

Owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the
cholinergic system. Across phyla, cholinergic signaling is essential for many neuro …

Rice–vegetable rotations are dominant in (sub)-tropical agriculture worldwide. However, fate
and risks of the insecticide flonicamid (FLO) and its main degradates (collectively called …

Flonicamid (N-cyanomethyl-4-trifluoromethylnicotinamide, FLO), a novel selective systemic
pyridinecarboxamide insecticide, effectively controls hemipterous pests. However, microbial …

The insecticide flonicamid (FLO) and its main degradation intermediate 4-
trifluoromethylnicotinamide (TFNA-AM) are hazardous to the environment and animals …

Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used
frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was …

Neonicotinoids have been among the most widely and abundantly used insecticides for
most of the current century. The effects of these substances on nontarget terrestrial and …

The amides 4-trifluoromethylnicotinamide, acrylamide, and benzamide are widely used in
agriculture and industry, posing hazards to the environment and animals. Immobilized …