Parkinson's disease is a common and disabling disorder of movement owing to
dopaminergic denervation of the striatum. However, it is still unclear how this denervation …

The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …

An important mechanism for large-scale interactions between cortical areas involves
coupling between the phase and the amplitude of different brain rhythms. Could basal …

Parkinson disease is a common neurodegenerative disorder that leads to difficulty in
effectively translating thought into action. Although it is known that dopaminergic neurons …

Neuronal substrates of brain disconnection during NREM sleep 3. Three types of brain
rhythms during NREM sleep: the unified corticothalamic system 3.1. Spindles, a thalamic …

Enhanced oscillations at beta frequencies (8–30 Hz) are a signature neural dynamic
pathology in the basal ganglia and cortex of Parkinson's disease patients. The mechanisms …

Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear
how membrane potentials of individual neurons track behavioral rhythms, even though …

Motor thalamus (Mthal) is implicated in the control of movement because it is strategically
located between motor areas of the cerebral cortex and motor-related subcortical structures …

Appetitive motivation and incentive states are essential functions sustained by a common
emotional brain process, the SEEKING disposition, which drives explorative and approach …

The striatum receives massive cortical excitatory inputs and is densely innervated by
dopamine. Striatal projection neurons form either the direct or indirect pathways. Models of …