Mitochondrial dysfunction as a signaling target for therapeutic intervention in major neurodegenerative disease

SV Mangrulkar, NL Wankhede, MB Kale… - Neurotoxicity …, 2023 - Springer
Neurodegenerative diseases (NDD) are incurable and the most prevalent cognitive and
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …

Unraveling the nexus of age, epilepsy, and mitochondria: exploring the dynamics of cellular energy and excitability

W Xie, S Koppula, MB Kale, LS Ali… - Frontiers in …, 2024 - frontiersin.org
Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly
recognized for its intricate relationship with mitochondria, the cellular powerhouses …

Mitophagy regulation in aging and neurodegenerative disease

TA Banarase, SS Sammeta, NL Wankhede… - Biophysical …, 2023 - Springer
Mitochondria are the primary cellular energy generators, supplying the majority of
adenosine triphosphate through oxidative phosphorylation, which is necessary for neuron …

Decoding the therapeutic potential of cannabis and cannabinoids in neurological disorders

MB Kale, MD Umare, NL Wankhede… - Current …, 2024 - benthamdirect.com
For millennia, Cannabis sativa has served diverse roles, from medicinal applications to
recreational use. Despite its extensive historical use, only a fraction of its components have …

[HTML][HTML] Modulation of mitochondrial function in elderly brain: Involvement of autophagy and apoptosis

P Chandurkar, M Dhokne, N Wankhede… - INNOSC Theranostics …, 2023 - accscience.com
Mitochondria are crucial cellular organelles that regulate energy production, oxidative
balance, and calcium homeostasis, among other things. Aging is a natural, multifactorial …

Mitochondrial Dysfunction in Neurodevelopmental Disorders: A Systematic Review on Pathways and Mechanisms

SV Gawali, VS Marde, NB Kale… - Current Indian …, 2023 - benthamdirect.com
Background Neurodevelopmental disorders (NDDs) are types of disorders that are marked
by a wide range of genetic and clinical mutability which will affect the development and …

Agmatine as a novel treatment option for neuropathies: experimental evidences

MD Dhokne, MP Dixit, MB Kale… - INNOSC Theranostics …, 2023 - accscience.com
N-methyl-D-aspartate receptor (NMDAR) antagonist, a subclass of glutamate receptors or
nitric oxide synthase (NOS) inhibitors, prevents neuronal plasticity. However, neural …

[PDF][PDF] Уровень малондиальдегида в крови женщин, подвергшихся радиационному воздействию в результате чернобыльской аварии

ТИ Иванова, ЛА Дзиковская, ВА Хорохорина… - researchgate.net
При хроническом радиационном воздействии в организме возможно развитие
окислительного стресса, ассоциированного со многими заболеваниями …