ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …

The endoplasmic reticulum (ER) has a quality-control system for'proof-reading'newly
synthesized proteins, so that only native conformers reach their final destinations. Non …

Protein folding in the endoplasmic reticulum (ER) is monitored by ER quality control (ERQC)
mechanisms. Proteins that pass ERQC criteria traffic to their final destinations through the …

Proteins synthesized in the endoplasmic reticulum (ER) are properly folded with the
assistance of ER chaperones. Malfolded proteins are disposed of by ER‐associated protein …

In eukaryotic cells, the endoplasmic reticulum (ER) is a membrane-enclosed interconnected
organelle responsible for the synthesis, folding, modification, and quality control of …

ER-phagy, literally endoplasmic reticulum (ER)-eating, defines the constitutive or regulated
clearance of ER portions within metazoan endolysosomes or yeast and plant vacuoles. The …

A substantial fraction of eukaryotic gene products are synthesized by ribosomes attached at
the cytosolic face of the endoplasmic reticulum (ER) membrane. These polypeptides enter …

Eukaryotic cells are able to discriminate between native and non‐native polypeptides,
selectively transporting the former to their final destinations. Secretory proteins are …

About 40% of the eukaryotic cell's proteins are inserted co-or post-translationally in the
endoplasmic reticulum (ER), where they attain the native structure under the assistance of …

Rising interest in the mechanism and function of the proteasomes and the ubiquitin system
revealed that it is hard to find any aspect of the cellular metabolic network that is not directly …