The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Animal behavior was classically considered to be determined exclusively by neuronal
activity, whereas surrounding glial cells such as astrocytes played only supportive roles …

d-amino acids, the enantiomeric counterparts of l-amino acids, were long considered to be
non-functional or not even present in living organisms. Nowadays, d-amino acids are …

Importance In addition to dopaminergic hyperactivity, hypofunction of theN-methyl-d-
aspartate receptor (NMDAR) has an important role in the pathophysiology of schizophrenia …

Alzheimer's disease (AD) is a severe neurodegenerative disorder still in search of effective
methods of diagnosis. Altered levels of the NMDA receptor co-agonist, d-serine, have been …

Assembly of synapses requires proper coordination between pre-and postsynaptic
elements. Identification of cellular and molecular events in synapse formation and …

D-Serine is a potent co-agonist at the NMDA glutamate receptor and has been the object of
many preclinical studies to ascertain the nature of its metabolism, its regional and cellular …

Alzheimer′ s disease (AD) is the most common form of dementia in the elderly. Memory
loss in AD is increasingly attributed to soluble oligomers of the amyloid‐β peptide (AβOs) …

Glutamatergic transmission in schizophrenia: from basic rese... : Current Opinion in Psychiatry
Glutamatergic transmission in schizophrenia: from basic research to clinical practice : Current …

The N-methyl-d-aspartate receptor (NMDAR) antagonists, phencyclidine (PCP), dizocilpine
(MK-801), or ketamine, given subchronically (sc) to rodents and primates, produce …