Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

A Verkhratsky, M Matteoli, V Parpura, JP Mothet… - The EMBO …, 2016 - embopress.org
Astrocytes are housekeepers of the central nervous system (CNS) and are important for
CNS development, homeostasis and defence. They communicate with neurones and other …

Neuron–glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

GK Sheridan, KJ Murphy - Open biology, 2013 - royalsocietypublishing.org
An essential aspect of normal brain function is the bidirectional interaction and
communication between neurons and neighbouring glial cells. To this end, the brain has …

Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for neural repair

O Avraham, R Feng, EE Ewan, J Rustenhoven, G Zhao… - Elife, 2021 - elifesciences.org
Sensory neurons with cell bodies in dorsal root ganglia (DRG) represent a useful model to
study axon regeneration. Whereas regeneration and functional recovery occurs after …

[HTML][HTML] Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation

T Zehnder, F Petrelli, J Romanos, ECDO Figueiredo… - Cell Reports, 2021 - cell.com
The mechanisms controlling the post-natal maturation of astrocytes play a crucial role in
ensuring correct synaptogenesis. We show that mitochondrial biogenesis in developing …

Gliotransmission and the tripartite synapse

M Santello, C Calì, P Bezzi - Synaptic plasticity: Dynamics, development …, 2012 - Springer
In the last years, the classical view of glial cells (in particular of astrocytes) as a simple
supportive cell for neurons has been replaced by a new vision in which glial cells are active …

Astrocyte physiopathology: at the crossroads of intercellular networking, inflammation and cell death

D Rossi - Progress in neurobiology, 2015 - Elsevier
Recent breakthroughs in neuroscience have led to the awareness that we should revise our
traditional mode of thinking and studying the CNS, ie by isolating the privileged network of …

Obesity affects the microbiota–gut–brain axis and the regulation thereof by endocannabinoids and related mediators

N Forte, AC Fernández-Rilo, L Palomba… - International Journal of …, 2020 - mdpi.com
The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …

Epigenetic modifications associated to neuroinflammation and neuropathic pain after neural trauma

C Penas, X Navarro - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Accumulating evidence suggests that epigenetic alterations lie behind the induction and
maintenance of neuropathic pain. Neuropathic pain is usually a chronic condition caused by …

Satellite Glial Cells: Morphology, functional heterogeneity, and role in pain

D Andreeva, L Murashova, N Burzak… - Frontiers in Cellular …, 2022 - frontiersin.org
Neurons in the somatic, sympathetic, and parasympathetic ganglia are surrounded by
envelopes consisting of satellite glial cells (SGCs). Recently, it has become clear that SGCs …