[HTML][HTML] Cell culture propagation of foot-and-mouth disease virus: Adaptive amino acid substitutions in structural proteins and their functional implications

V Dill, M Eschbaumer - Virus Genes, 2020 - Springer
Foot-and-mouth disease is endemic in livestock in large parts of Africa and Asia, where it is
an important driver of food insecurity and a major obstacle to agricultural development and …

[HTML][HTML] Cell Culture Adaptive Amino Acid Substitutions in FMDV Structural Proteins: A Key Mechanism for Altered Receptor Tropism

H Mushtaq, SS Shah, Y Zarlashat, M Iqbal, W Abbas - Viruses, 2024 - mdpi.com
The foot-and-mouth disease virus is a highly contagious and economically devastating virus
of cloven-hooved animals, including cattle, buffalo, sheep, and goats, causing reduced …

[HTML][HTML] A vaccine strain of the A/ASIA/Sea-97 lineage of foot-and-mouth disease virus with a single amino acid substitution in the P1 region that is adapted to …

JH Hwang, G Lee, A Kim, JH Park, MJ Lee, B Kim… - Vaccines, 2021 - mdpi.com
There are seven viral serotypes of foot-and-mouth disease virus (FMDV): A, O, C, Asia 1,
and Southern African Territories 1, 2, and 3 (SAT 1–3). Unlike serotype O FMDV vaccine …

Epidemiological Surveillance and Mutational Pattern Analysis of Foot‐and‐Mouth Disease Outbreaks in Bangladesh during 2012–2021

KA Hossain, H Anjume, M Akther… - Transboundary and …, 2023 - Wiley Online Library
Foot‐and‐mouth disease (FMD) in cloven‐hoofed animals is considered an economically
devastating disease in endemic countries like Bangladesh, where the livestock sector …

[HTML][HTML] Identification of antibody-resistant SARS-CoV-2 mutants via N4-Hydroxycytidine mutagenesis

P Kumar, X Zhang, R Shaha, M Kschischo… - Antiviral Research, 2024 - Elsevier
Monoclonal antibodies targeting the Spike protein of SARS-CoV-2 are effective against
COVID-19 and might mitigate future pandemics. However, their efficacy is challenged by the …

Cell culture adaptation mutations in foot-and-mouth disease virus serotype A capsid proteins: implications for receptor interactions

JK Mohapatra, LK Pandey, DK Rai… - Journal of General …, 2015 - microbiologyresearch.org
In this study we describe the adaptive changes fixed on the capsid of several foot-and-mouth
disease virus serotype A strains during propagation in cell monolayers. Viruses passaged …

A recombinant multi-epitope trivalent vaccine for foot-and-mouth disease virus serotype O in pigs

J Shao, W Liu, S Gao, H Chang, H Guo - Virology, 2024 - Elsevier
In order to develop a safe and effective broad-spectrum vaccine for foot-and-mouth disease
(FMDV), here, we developed a recombinant FMD multiple-epitope trivalent vaccine based …

A positively charged lysine residue at VP2 131 position allows for the enhanced adaptability of foot-and-mouth disease virus serotype A in BHK-21 cells

JK Biswal, JK Mohapatra, P Bisht, S Subramaniam… - Biologicals, 2015 - Elsevier
Field outbreak strains of foot-and-mouth disease virus (FMDV) infect host cells through
certain Arg-Gly-Asp (RGD) dependent integrin family of cellular receptors. In contrast, FMDV …

Evolution of foot-and-mouth disease virus serotype A capsid coding (P1) region on a timescale of three decades in an endemic context

B Das, JK Mohapatra, V Pande, S Subramaniam… - Infection, Genetics and …, 2016 - Elsevier
Abstract Three decades-long (1977–2013) evolutionary trend of the capsid coding (P1)
region of foot-and-mouth disease virus (FMDV) serotype A isolated in India was analysed …

Selective isolation of foot-and-mouth disease virus from coinfected samples containing more than one serotype

S Mahajan, GK Sharma, S Subramaniam… - Brazilian Journal of …, 2021 - Springer
The foot-and-mouth disease virus (FMDV) causes a highly infectious disease of all cloven-
footed animals. The RNA genome of the virus continuously evolves, leading to the …