Importance Glaucoma is the most common cause of irreversible blindness worldwide. Many
patients with glaucoma are asymptomatic early in the disease course. Primary care …

The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Glaucoma, a diverse group of eye disorders that results in the degeneration of retinal
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …

Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial …

Glaucoma, a group of diseases characterized by progressive optic nerve degeneration that
results in irreversible blindness, can be considered a neurodegenerative disorder of both …

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness
worldwide, disproportionately affects individuals of African ancestry. We conducted a …

Effective population screening for glaucoma would enable earlier diagnosis and prevention
of irreversible vision loss. The UK National Screening Committee (NSC) recently published …

Genome-wide association studies (GWASs) of eye disorders have identified hundreds of
genetic variants associated with ocular disease. However, the vast majority of these variants …

Glaucoma is the leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common glaucoma subtype, is more prevalent and severe in …

Purpose: POAG is the leading cause of irreversible blindness in African Americans. In this
study, we quantitatively assess the association of autosomal ancestry with POAG risk in a …