An updated review on developing small molecule kinase inhibitors using computer-aided drug design approaches
L Li, S Liu, B Wang, F Liu, S Xu, P Li… - International Journal of …, 2023 - mdpi.com
Small molecule kinase inhibitors (SMKIs) are of heightened interest in the field of drug
research and development. There are 79 (as of July 2023) small molecule kinase inhibitors …
research and development. There are 79 (as of July 2023) small molecule kinase inhibitors …
Recent updates on pyrazoline derivatives as promising candidates for neuropsychiatric and neurodegenerative disorders
TM Rangarajan, B Mathew - Current Topics in Medicinal …, 2021 - ingentaconnect.com
Pyrazolines are five-membered heterocyclic compounds containing two nitrogen atoms that
represent a privileged scaffold for various bioactive compounds with diverse …
represent a privileged scaffold for various bioactive compounds with diverse …
Synthesis and evaluation of new pyrazoline‐thiazole derivatives as monoamine oxidase inhibitors
Abstract A novel series of 1, 3, 5‐trisubstituted‐2‐pyrazoline derivatives (4a‐4k) was
synthesized and their chemical structures characterized by 1H NMR, 13C NMR, and mass …
synthesized and their chemical structures characterized by 1H NMR, 13C NMR, and mass …
Design, Synthesis and hMAO inhibitory screening of novel 2-pyrazoline analogues
B Evranos-Aksoz, G Ucar… - … Chemistry & High …, 2017 - ingentaconnect.com
Aim and Objective: MAO inhibitors have a significant effect on the nervous system since they
act in regulation of neurotransmitter concentrations. Neurotransmitter levels are critical for a …
act in regulation of neurotransmitter concentrations. Neurotransmitter levels are critical for a …
Synthesis and biological evaluation of some pyrazole derivatives, containing (Thio) semicarbazide, as dual anti-inflammatory antimicrobial agents
Z Liang, Y Huang, S Wang… - Letters in Drug Design & …, 2019 - ingentaconnect.com
Background: Several series of pyrazole derivatives containing (thio) semicarbazide (4a-4h,
5a-5l, 6a-6f, 7a-7c) were designed and synthesized to screen dual inflammatory and …
5a-5l, 6a-6f, 7a-7c) were designed and synthesized to screen dual inflammatory and …
Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational …
GE Mathew, JM Oh, K Mohan, MV Kumudhavalli… - Process …, 2020 - Elsevier
A series of eleven 1-methyl, 5-phenyl substituted thiosemicarbazones (MT1–MT11) with the
phenyl ring substitutions were prepared and investigated for their inhibitory activities against …
phenyl ring substitutions were prepared and investigated for their inhibitory activities against …
1, 3, 5-triaril-4, 5-dihidro-1h-pirazol türevi bazı bileşiklerin benzodiazepin reseptörleri aracılıklı anksiyolitik-benzeri etkileri
Amaç: Pirazol, üç karbon atomundan ve yan yana iki azot atomundan oluşan beş üyeli
heterosiklik bir halka sistemidir. Literatürde pirazol çekirdeği taşıyan kimyasal bileşiklerin …
heterosiklik bir halka sistemidir. Literatürde pirazol çekirdeği taşıyan kimyasal bileşiklerin …
Antinociceptive activities of some 4, 5-dihydro-1H-pyrazole derivatives: Involvement of central and peripheral pathways
This study was planned to investigate possible antinociceptive activity of 1, 5-diaryl-3-[4-
(methylsulfonyl) phenyl]-4, 5-dihydro-1H-pyrazole derivatives (2a-s), based on the analgesia …
(methylsulfonyl) phenyl]-4, 5-dihydro-1H-pyrazole derivatives (2a-s), based on the analgesia …
The crystal structure of 1-phenyl-N-(4, 5, 6, 7-tetrabromo-1, 3-dioxoisoindolin-2-yl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamide-dimethylformamide (1/1) …
MA Baashen, BF Abdel-Wahab, AS Hegazy… - … New Crystal Structures, 2021 - degruyter.com
The crystal structure of 1-phenyl-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxamide-dimethylformamide
(1/1) C22H10Br4N4O3S Skip to content Should you have institutional access? Here's how …
(1/1) C22H10Br4N4O3S Skip to content Should you have institutional access? Here's how …
and Gamal A. El-Hiti
Zeitschrift für Kristallographie - New Crystal Structures Page 1 Mohammed A.
Baashen, Bakr F. Abdel-Wahab, Amany S. Hegazy, Benson M. Kariuki and Gamal A. El-Hiti …
Baashen, Bakr F. Abdel-Wahab, Amany S. Hegazy, Benson M. Kariuki and Gamal A. El-Hiti …