Neuronal nicotinic acetylcholine (nACh) receptors in the brain are more commonly
associated with modulatory events than mediation of synaptic transmission. nACh receptors …

A series of human and animal investigations has suggested that altered expression and
function of the α7-nicotinic cholinergic receptor may be responsible for the auditory sensory …

Excessive inflammation and tumour-necrosis factor (TNF) synthesis cause morbidity and
mortality in diverse human diseases including endotoxaemia, sepsis, rheumatoid arthritis …

A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an
adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the …

This study tests the hypothesis that nicotinic cholinergic receptors, including those sensitive
to the antagonist α-bungarotoxin, are decreased in the hippocampus of schizophrenics. The …

NICOTINE obtained from tobacco can improve learning and memory on various tasks and
has been linked to arousal, attention, rapid information processing, working memory, and …

Reviews the literature on how the behavioral, cognitive, and addictive effects of nicotine can
be reconciled with the paucity of evidence for CNS synapses where the transmission is …

Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …

The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously
expressed in both the central nervous system and in the periphery. CHRNA7 is genetically …

PATHFINDING by growing nerve processes in the developing nervous system depends on
the turning response of the growing tip, the growth cone, to extracellular guidance cues1–4 …