This paper considers the role of putative adipokines that might be involved in the enhanced
inflammatory response of human adipose tissue seen in obesity. Inflammatory adipokines [IL …

2. Methodology......................................................... 2.1. Inhibition Assays..........................................
....... 2.2. Reduction Assays................................................. 2.3. Hydrophobic …

Background—Glutathione peroxidase-3 (GPx-3) is a selenocysteine-containing plasma
protein that scavenges reactive oxygen species in the extracellular compartment. A …

Arterial thrombosis is a complex disorder that involves multiple genetic and environmental
factors interacting to produce the characteristic phenotype. In the past decades, investigators …

Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing protein with
antioxidant properties. GPx-3 deficiency has been associated with cardiovascular disease …

Platelets play an important role in coagulation, in maintenance of hemostasis, and in the
pathophysiology of thrombotic diseases. In response to blood vessel injury, platelets …

Background and Purpose—Plasma glutathione peroxidase (GPx-3)–deficiency increases
extracellular oxidant stress, decreases bioavailable nitric oxide, and promotes platelet …

Purpose Retinal vascular caliber has been linked with increased cardiovascular risk and is
predictive of cardiovascular pathology, including stroke and coronary heart disease …

Background Since oxidized LDL is thought to initiate atherosclerosis and the serum
glutathione peroxidase (GPx3) reduces oxidized lipids, we investigated whether high GPx3 …

The possible involvement of oxidative damage in the progression of atherosclerosis has
been suggested. There is some evidence that antioxidant therapy may be beneficial for the …