[HTML][HTML] Lonicerae japonicae flos and Lonicerae flos: a systematic review of ethnopharmacology, phytochemistry and pharmacology

Y Li, W Li, C Fu, Y Song, Q Fu - Phytochemistry Reviews, 2020 - Springer
Lonicerae japonicae flos (called Jinyinhua, JYH in Chinese), flowers or flower buds of
Lonicera japonica Thunberg, is an extremely used traditional edible-medicinal herb …

Screening techniques for the identification of bioactive compounds in natural products

Y Fu, J Luo, J Qin, M Yang - Journal of pharmaceutical and biomedical …, 2019 - Elsevier
Natural products (NPs) have a long history of clinical use and are rich source of bioactive
compounds. The development of tools and techniques for identifying and analyzing NP …

Magnetic particles for enzyme immobilization: a versatile support for ligand screening

IAT Ximenes, PCO de Oliveira, CA Wegermann… - … of pharmaceutical and …, 2021 - Elsevier
Enzyme inhibitors represent a substantial fraction of all small molecules currently in clinical
use. Therefore, the early stage of drug-discovery process and development efforts are …

[HTML][HTML] Recent advances in screening active components from natural products based on bioaffinity techniques

X Hou, M Sun, T Bao, X Xie, F Wei, S Wang - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Natural products have provided numerous lead compounds for drug discovery. However,
the traditional analytical methods cannot detect most of these active components, especially …

Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined with liquid …

L Wang, Y Zhao, Y Zhang, T Zhang, J Kool… - … of Chromatography A, 2018 - Elsevier
In order to develop a direct and reliable method for discovering lead compounds from
traditional Chinese medicines (TCMs), a comparative online ligand fishing platform was …

[HTML][HTML] Chemical characterization, α-Glucosidase, α-amylase and lipase inhibitory properties of the Australian honey bee propolis

S Uddin, PR Brooks, TD Tran - Foods, 2022 - mdpi.com
The use of functional foods and nutraceuticals as a complementary therapy for the
prevention and management of type 2 diabetes and obesity has steadily increased over the …

Recent advances in bio-affinity chromatography for screening bioactive compounds from natural products

J Guo, H Lin, J Wang, Y Lin, T Zhang, Z Jiang - Journal of Pharmaceutical …, 2019 - Elsevier
Natural products are one of the most important sources of leading compounds in drug
discovery. Until now, rapid screening and identification of biologically active components …

Rapid and comprehensive profiling of α-glucosidase inhibitors in Buddleja Flos by ultrafiltration HPLC–QTOF-MS/MS with diagnostic ions filtering strategy

L Xie, Q Fu, S Shi, J Li, X Zhou - Food Chemistry, 2021 - Elsevier
Buddleja Flos is used as yellow rice colorant and a well-known traditional Chinese
medicine. But its biochemical profiling is still lack due to complex matrix. Here, ultrafiltration …

Off-line and on-line liquid chromatography-mass spectrometry methods with immobilized bio-macromolecules for drug screening from natural sources

Y Ping, L Zhang, X Wang, A Van Schepdael - Journal of Chromatography A, 2022 - Elsevier
Natural products are an important source of major compounds in drug discovery. Currently,
rapid screening and identification of bioactive compounds is a challenge due to the …

Rapid screening of α‐glucosidase inhibitors in Hypericum perforatum L. using bio‐affinity chromatography coupled with UPLC/MS

Q Dong, N Hu, H Yue, H Wang… - Biomedical …, 2023 - Wiley Online Library
Abstract α‐glucosidase inhibitors (AGIs) are widely used for the treatment of type 2 diabetes,
but their side effects have made it to develop novel and alternative AGIs immediately. In this …