Extracellular vesicles (EVs) are naturally occurring nanoparticles released from all
eucaryotic and procaryotic cells. While their role was formerly largely underestimated, EVs …

Osteoarthritis (OA) of joints such as the knee and hip are very prevalent, and the number of
individuals affected is expected to continue to rise. Currently, conservative treatments after …

Background Following an ischemic injury to the brain, the induction of angiogenesis is
critical to neurological recovery. The angiogenic benefits of mesenchymal stem cells (MSCs) …

Human mesenchymal stem cells (hMSCs) are multipotent cells and an attractive therapeutic
agent in regenerative medicine and intensive clinical research. Despite the great potential …

MicroRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression
by targeting mRNA. Moreover, it has been shown that miRNAs expression are changed in …

In the past decade, extracellular vesicles (EVs) have emerged as key regulators of bone
development, homeostasis and repair. EV-based therapies have the potential to …

Mesenchymal stem cells (MSCs) have been studied for decades as candidates for cellular
therapy, and their secretome, including secreted extracellular vesicles (EVs), has been …

Bone–muscle crosstalk is enabled thanks to the integration of different molecular signals,
and it is essential for maintaining the homeostasis of skeletal and muscle tissue. Both the …

The nasal septal cartilage plays an important role in preventing the collapse of the nasal
bones and maintaining the appearance of the nose. In the context of inherent difficulties …

Osteoarthritis is a multifactorial disease characterized by cartilage degeneration, while
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …